Protective mechanisms of end-ischemic cold machine perfusion in DCD liver grafts
A Schlegel, O De Rougemont, R Graf, PA Clavien… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: The aim of this study was to identify protective mechanisms of cold
machine perfusion in liver grafts donated after cardiac death. METHODS: Pig livers exposed
to 60-min warm ischemia were cold stored for 7h or treated after 6-h cold storage with 1-h
hypothermic oxygenated perfusion (HOPE) through the portal vein. Different physical
(perfusion pressure) and chemical (oxygen, mitochondrial transition pore inhibition)
parameters were analyzed during machine perfusion to dissect key steps of mechanism …
machine perfusion in liver grafts donated after cardiac death. METHODS: Pig livers exposed
to 60-min warm ischemia were cold stored for 7h or treated after 6-h cold storage with 1-h
hypothermic oxygenated perfusion (HOPE) through the portal vein. Different physical
(perfusion pressure) and chemical (oxygen, mitochondrial transition pore inhibition)
parameters were analyzed during machine perfusion to dissect key steps of mechanism …
以上显示的是最相近的搜索结果。 查看全部搜索结果