Quinolizidine alkaloids with anti-HBV activity from Sophora tonkinensis
PL Ding, H Huang, P Zhou, DF Chen - Planta medica, 2006 - thieme-connect.com
A new matrine-type alkaloid,(-)-14β-hydroxyoxymatrine (1), was isolated from the roots and
rhizomes of Sophora tonkinensis Gapnep.(Leguminosae), together with five known matrine-
type alkaloids,(-)-14β-hydroxymatrine (2),(+)-oxymatrine (3),(+)-matrine (4),(+)-sophoranol
(5), and (-)-5α-hydroxysophocarpine (6), as well as with two known cytisine-type alkaloids,(-)-
cytisine (7) and (-)-N-methylcytisine (8). Their structures were elucidated by spectroscopic
methods. Compounds 1, 5 and 7 showed potent anti-HBV activity with an inhibitory potency …
rhizomes of Sophora tonkinensis Gapnep.(Leguminosae), together with five known matrine-
type alkaloids,(-)-14β-hydroxymatrine (2),(+)-oxymatrine (3),(+)-matrine (4),(+)-sophoranol
(5), and (-)-5α-hydroxysophocarpine (6), as well as with two known cytisine-type alkaloids,(-)-
cytisine (7) and (-)-N-methylcytisine (8). Their structures were elucidated by spectroscopic
methods. Compounds 1, 5 and 7 showed potent anti-HBV activity with an inhibitory potency …
Quinolizidine alkaloids with anti-HBV activity from Sophora tonkinensis.
DPL Ding PeiLan, HH Huang Hai, ZP Zhou Pei… - 2006 - cabidigitallibrary.org
A new matrine-type alkaloid,(-)-14β-hydroxyoxymatrine (1), was isolated from the roots and
rhizomes of Sophora tonkinensis Gapnep.(Leguminosae), together with five known matrine-
type alkaloids,(-)-14β-hydroxymatrine (2),(+)-oxymatrine (3),(+)-matrine (4),(+)-sophoranol
(5), and (-)-5α-hydroxysophocarpine (6), as well as with two known cytisine-type alkaloids,(-)-
cytisine (7) and (-)-N-methylcytisine (8). Their structures were elucidated by spectroscopic
methods. Compounds 1, 5 and 7 showed potent anti-HBV activity with an inhibitory potency …
rhizomes of Sophora tonkinensis Gapnep.(Leguminosae), together with five known matrine-
type alkaloids,(-)-14β-hydroxymatrine (2),(+)-oxymatrine (3),(+)-matrine (4),(+)-sophoranol
(5), and (-)-5α-hydroxysophocarpine (6), as well as with two known cytisine-type alkaloids,(-)-
cytisine (7) and (-)-N-methylcytisine (8). Their structures were elucidated by spectroscopic
methods. Compounds 1, 5 and 7 showed potent anti-HBV activity with an inhibitory potency …
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