[HTML][HTML] ROCK2 regulates monocyte migration and cell to cell adhesion in vascular endothelial cells
Y Takeda, K Matoba, D Kawanami, Y Nagai… - International journal of …, 2019 - mdpi.com
The small GTPase Rho and its downstream effector, Rho-kinase (ROCK), regulate various
cellular functions, including organization of the actin cytoskeleton, cell adhesion and
migration. A pro-inflammatory lipid mediator, lysophosphatidic acid (LPA), is a potent
activator of the Rho/ROCK signalling pathway and has been shown to induce the
expression of chemokines and cell adhesion molecules (CAMs). In the present study, we
aimed to elucidate the precise mechanism by which ROCK regulates LPA-induced …
cellular functions, including organization of the actin cytoskeleton, cell adhesion and
migration. A pro-inflammatory lipid mediator, lysophosphatidic acid (LPA), is a potent
activator of the Rho/ROCK signalling pathway and has been shown to induce the
expression of chemokines and cell adhesion molecules (CAMs). In the present study, we
aimed to elucidate the precise mechanism by which ROCK regulates LPA-induced …
ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells.
竹田裕介 - International journal of molecular sciences, 2021 - ir.jikei.ac.jp
The small GTPase Rho and its downstream effector, Rho-kinase (ROCK), regulate various
cellular functions, including organization of the actin cytoskeleton, cell adhesion and
migration. A pro-inflammatory lipid mediator, lysophosphatidic acid (LPA), is a potent
activator of the Rho/ROCK signalling pathway and has been shown to induce the
expression of chemokines and cell adhesion molecules (CAMs). In the present study, we
aimed to elucidate the precise mechanism by which ROCK regulates LPA-induced …
cellular functions, including organization of the actin cytoskeleton, cell adhesion and
migration. A pro-inflammatory lipid mediator, lysophosphatidic acid (LPA), is a potent
activator of the Rho/ROCK signalling pathway and has been shown to induce the
expression of chemokines and cell adhesion molecules (CAMs). In the present study, we
aimed to elucidate the precise mechanism by which ROCK regulates LPA-induced …
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