Randomized, clinical trial comparison of trisodium citrate 30% and heparin as catheter-locking solution in hemodialysis patients

MC Weijmer, MA Van Den Dorpel… - Journal of the …, 2005 - journals.lww.com
Interdialytic hemodialysis catheter-locking solutions could contribute to a reduction of
catheter-related complications, especially infections. However, they can cause side effects
because of leakage from the tip of the catheter. Recently, trisodium citrate (TSC) has been
advocated because of its antimicrobial properties and local anticoagulation. In a multicenter,
double-blind, randomized, controlled trial, TSC 30% was compared with unfractionated
heparin 5000 U/ml for prevention of catheter-related infections, thrombosis, and bleeding …
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