Recent Progress for the Synthesis of β-Carboline Derivatives–an Update
Polycyclic Aromatic Compounds, 2024•Taylor & Francis
The β-Carboline and its derivatives are privileged heterocyclic motifs and important building
blocks in the field of medicinal chemistry due to their remarkable pharmacological
potentialities and their derivatives have attracted a great deal of interest due to their wide
range of biological activities. β-Carboline contains tricyclic pyrido [3, 4-b] indole moiety in
their structure. The growing potential inherent in them encourages many researchers to
address the challenges of the synthesis of β-Carboline framework. As a result, many …
blocks in the field of medicinal chemistry due to their remarkable pharmacological
potentialities and their derivatives have attracted a great deal of interest due to their wide
range of biological activities. β-Carboline contains tricyclic pyrido [3, 4-b] indole moiety in
their structure. The growing potential inherent in them encourages many researchers to
address the challenges of the synthesis of β-Carboline framework. As a result, many …
Abstract
The β-Carboline and its derivatives are privileged heterocyclic motifs and important building blocks in the field of medicinal chemistry due to their remarkable pharmacological potentialities and their derivatives have attracted a great deal of interest due to their wide range of biological activities. β-Carboline contains tricyclic pyrido[3,4-b]indole moiety in their structure. The growing potential inherent in them encourages many researchers to address the challenges of the synthesis of β-Carboline framework. As a result, many methodologies have been developed to synthesize this important class of compounds. The present review is mainly an attempt to present the research work reported in the recent scientific literature focusing on different synthetic methods of β-Carboline and related derivatives.
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