Recent advances in the effects of dietary polyphenols on inflammation in vivo: Potential molecular mechanisms, receptor targets, safety issues, and uses of …

D Wang, T Wang, Z Zhang, Z Li, Y Guo, G Zhao… - Current Opinion in Food …, 2022 - Elsevier
High dietary intake of dietary polyphenols is associated with a decreased risk of chronic
diseases, especially in inflammation. However, mechanisms responsible for their anti-
inflammatory effect in vivo are still not fully understood. Many animal studies showed the
beneficial effects of polyphenols on inflammation, but in clinical trials the results were
variable, some of them are negative. Despite the initial successes demonstrated in animal
and early clinical trials regarding the safety and efficacy of polyphenols, a number of …
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