Chikungunya fever has become an important public health problem in countries where
epidemics occur because half of the cases progress to chronic, persistent and debilitating
arthritis. Literature data on specific therapies at the various phases of arthropathy caused by
chikungunya virus (CHIKV) infection are limited, lacking quality randomized trials assessing
the efficacies of different therapies. There are a few studies on the treatment of
musculoskeletal manifestations of chikungunya fever, but these studies have important …

Chikungunya fever has become a relevant public health problem in countries where
epidemics occur. Until 2013, only imported cases occurred in the Americas, but in October of
that year, the first cases were reported in Saint Marin island in the Caribbean. The first
autochthonous cases were confirmed in Brazil in September 2014; until epidemiological
week 37 of 2016, 236,287 probable cases of infection with Chikungunya virus had been
registered, 116,523 of which had serological confirmation. Environmental changes caused …