… Soon, manufacturers combined these cellular pertussis vaccines with diphtheria (DTx) and
tetanus toxoids (TTx) adsorbed onto alum (DTPads). DTPads was recommended for routine …

… CMI responses were mixed T H 1/T H 2 type by cytokine profile for all antigens. Injection site
… doses, 17,26 consistent with the notion that a reduced antigen stimulus might reduce cell-…

… In 1948, whole-cell pertussis vaccine combined with diphtheria and tetanus toxoid (DTP) …
Reduced-antigen, combined diphtheria, tetanus and acellular pertussis vaccine, adsorbed (…

… of booster doses, acellular pertussis combination vaccines remain the preferred vaccines for
preventing pertussis, diphtheria, and tetanus … with whole-cell pertussis vaccines. However, …

… , one is adsorbed and is licensed for use in situations in which the combined antigen preparation
… is a fluid vaccine (not adsorbed) and is indicated only for booster doses, not for primary …

… alone or in combination with tetanus toxoid (TT) and diphtheria toxoid (DT). The 3 … aP and
tetanus-diphtheria-acellular pertussis (TdaP; adsorbed, reduced antigen content) vaccines, …

… Pertussis in adults and adolescents could therefore be reduced by replacing traditional
Td boosters with reduced-antigen content acellular pertussis, diphtheria and tetanus (dTpa) …

… pertussis vaccine, which was first licensed in the US in 1914, and was combined with tetanus
and diphtheria toxoids (DTP vaccine… the current alum-absorbed aP vaccines delivered with …

… a range of combined vaccine products, including those with a reduced antigen dose. The
assay can be applied directly to non-adsorbed vaccines to measure the total diphtheria antigen …

… booster dose of reduced antigen content diphtheria, tetanus, acellular pertussis vaccine (…
persist until adolescence after a reduced-antigen diphtheria, tetanus and acellular pertussis …