Real-time TDM-based expert clinical pharmacological advice program for attaining aggressive pharmacokinetic/pharmacodynamic target of continuous infusion …

M Gatti, M Rinaldi, T Tonetti, A Siniscalchi, P Viale… - Antibiotics, 2023 - mdpi.com
(1) Objectives: to describe the pharmacokinetic/pharmacodynamic (PK/PD) profile of
continuous infusion (CI) meropenem in critical patients with documented Gram-negative
infections undergoing continuous veno-venous hemodiafiltration (CVVHDF) and to assess
the relationship with microbiological outcome.(2) Methods: Data were retrospectively
retrieved for patients admitted to the general and the post-transplant intensive care units in
the period October 2022–May 2023 who underwent CVVHDF during treatment with CI …

Role of a real-time TDM-based expert clinical pharmacological advice program in optimizing the early pharmacokinetic/pharmacodynamic target attainment of …

M Gatti, M Rinaldi, C Laici, A Siniscalchi, P Viale, F Pea - Antibiotics, 2023 - mdpi.com
(1) Objectives: To describe the attainment of optimal pharmacokinetic/pharmacodynamic
(PK/PD) targets in orthotopic liver transplant (OLT) recipients treated with continuous
infusion (CI) beta-lactams optimized using a real-time therapeutic drug monitoring (TDM)-
guided expert clinical pharmacological advice (ECPA) program during the early post-
surgical period.(2) Methods: OLT recipients admitted to the post-transplant intensive care
unit over the period of July 2021–September 2023, receiving empirical or targeted therapy …
以上显示的是最相近的搜索结果。 查看全部搜索结果