[HTML][HTML] STLV-1 as a model for studying HTLV-1 infection
B Jégado, F Kashanchi, H Dutartre, R Mahieux - Retrovirology, 2019 - Springer
B Jégado, F Kashanchi, H Dutartre, R Mahieux
Retrovirology, 2019•SpringerFew years after HTLV-1 identification and isolation in humans, STLV-1, its simian
counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian
species. Subsequent molecular epidemiology studies demonstrated that, apart from HTLV-1
subtype A, all human subtypes have a simian homolog. As HTLV-1, STLV-1 is the etiological
agent of ATL, while no case of TSP/HAM has been described. Given its similarities with
HTLV-1, STLV-1 represents a unique tool used for performing clinical studies, vaccine …
counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian
species. Subsequent molecular epidemiology studies demonstrated that, apart from HTLV-1
subtype A, all human subtypes have a simian homolog. As HTLV-1, STLV-1 is the etiological
agent of ATL, while no case of TSP/HAM has been described. Given its similarities with
HTLV-1, STLV-1 represents a unique tool used for performing clinical studies, vaccine …
Abstract
Few years after HTLV-1 identification and isolation in humans, STLV-1, its simian counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian species. Subsequent molecular epidemiology studies demonstrated that, apart from HTLV-1 subtype A, all human subtypes have a simian homolog. As HTLV-1, STLV-1 is the etiological agent of ATL, while no case of TSP/HAM has been described. Given its similarities with HTLV-1, STLV-1 represents a unique tool used for performing clinical studies, vaccine studies as well as basic science.
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