Simultaneous determination of trifolirhizin, (–)‐maackiain, (–)‐sophoranone, and 2‐(2,4‐dihydroxyphenyl)‐5,6‐methylenedioxybenzofuran from Sophora tonkinensis …

H Yoo, KH Ryu, SK Bae, J Kim - Journal of separation science, 2014 - Wiley Online Library
A new liquid chromatography with tandem mass spectrometry method was developed and
validated for the simultaneous determination of trifolirhizin,(–)‐maackiain,(–)‐sophoranone,
and 2‐(2, 4‐dihydroxyphenyl)‐5, 6‐methylenedioxybenzofuran from Sophora tonkinensis in
rat plasma using chlorpropamide as an internal standard. Plasma samples (50 μL) were
prepared using a simple deproteinization procedure with 150 μL of acetonitrile containing
100 ng/mL of chlorpropamide. Chromatographic separation was carried out on an Acclaim …

Simultaneous determination of trifolirhizin, (-)-maackiain, (-)-sophoranone, and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran from Sophora tonkinensis in …

YHS Yoo HunSeung, RKH Ryu KeunHo… - 2014 - cabidigitallibrary.org
A new liquid chromatography with tandem mass spectrometry method was developed and
validated for the simultaneous determination of trifolirhizin,(-)-maackiain,(-)-sophoranone,
and 2-(2, 4-dihydroxyphenyl)-5, 6-methylenedioxybenzofuran from Sophora tonkinensis in
rat plasma using chlorpropamide as an internal standard. Plasma samples (50 µL) were
prepared using a simple deproteinization procedure with 150 µL of acetonitrile containing
100 ng/mL of chlorpropamide. Chromatographic separation was carried out on an Acclaim …
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