[HTML][HTML] Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility
… used authentic SARS-CoV-2 to demonstrate that spike substitution D614G enhances viral
replication in the upper respiratory tract and increases neutralization susceptibility. These …
replication in the upper respiratory tract and increases neutralization susceptibility. These …
[HTML][HTML] Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility
… A spike protein mutation D614G emerged and became dominant soon … D614G mutation
into an authentic wild-type SARS-CoV-2 strain, we demonstrate the importance of this mutation …
into an authentic wild-type SARS-CoV-2 strain, we demonstrate the importance of this mutation …
[HTML][HTML] Spike mutation D614G alters SARS-CoV-2 fitness
… authentic SARS-CoV-2 to demonstrate that the spike D614G … tract and increases the
susceptibility of the virus to neutralization by … on other emerging mutations in SARS-CoV-2, …
susceptibility of the virus to neutralization by … on other emerging mutations in SARS-CoV-2, …
[HTML][HTML] D614G spike mutation increases SARS CoV-2 susceptibility to neutralization
… coronavirus 2 (SARS-CoV-2) spike protein acquired a D614G mutation early in … D614G
might also mediate neutralization escape that could compromise vaccine efficacy, sera from spike…
might also mediate neutralization escape that could compromise vaccine efficacy, sera from spike…
[HTML][HTML] D614G mutation and SARS-CoV-2: impact on S-protein structure, function, infectivity, and immunity
… changes are observed in SARS-CoV-2 variants due to the … of the SARS-CoV-2 genome
contained the aspartic acid in spike … some of the conformations, giving some extra fitness to the …
contained the aspartic acid in spike … some of the conformations, giving some extra fitness to the …
[HTML][HTML] Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant
… Emerging variants of SARS-CoV-2 that harbor genome mutations that may impact … mutations
across the genome, including several in the receptor-binding domain (RBD) of the spike …
across the genome, including several in the receptor-binding domain (RBD) of the spike …
[HTML][HTML] … of the N501Y, E484K/Q, K417N/T, L452R and T478K mutations on the SARS-CoV-2 spike protein RBD and its influence on agent fitness and on attributes …
RAA Pondé - Virology, 2022 - Elsevier
… L452R mutation with D614G and with the D614G mutation … by 13 amino acid changes,
contain diverse mutations in the … escape, transmissibility, and susceptibility to some treatments, …
contain diverse mutations in the … escape, transmissibility, and susceptibility to some treatments, …
[HTML][HTML] Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation
… and susceptibility to antibody neutralization associated with … SARS-CoV-2 spike pseudoviruses
carrying D614G alone or … conformational changes in the RBD that impact neutralizing …
carrying D614G alone or … conformational changes in the RBD that impact neutralizing …
Functional importance of the D614G mutation in the SARS-CoV-2 spike protein
… -residue mutations will not likely change viral sensitivity to neutralization unless they grossly
alter S … , which confers an apparent fitness advantage to the virus. It is not certain whether …
alter S … , which confers an apparent fitness advantage to the virus. It is not certain whether …
[HTML][HTML] Are the emerging SARS-COV-2 mutations friend or foe?
A Erol - Immunology Letters, 2021 - ncbi.nlm.nih.gov
… does not alter significantly SARS-CoV-2 morphology, spike … susceptible to neutralization
by host antibody responses as a consequence of acquiring a mutation that provides a fitness …
by host antibody responses as a consequence of acquiring a mutation that provides a fitness …