Stereotactic radiosurgery for pediatric brain arteriovenous malformations: long-term outcomes

CJ Chen, CC Lee, H Kano, KN Kearns, D Ding… - Journal of …, 2020 - thejns.org
OBJECTIVE Contrary to the better described obliteration-and hemorrhage-related data after
stereotactic radiosurgery (SRS) of brain arteriovenous malformations (AVMs) in pediatric
patients, estimates of the rarer complications, including cyst and tumor formation, are limited
in the literature. The aim of the present study was to assess the long-term outcomes and
risks of SRS for AVMs in pediatric patients (age< 18 years). METHODS The authors
retrospectively analyzed the International Radiosurgery Research Foundation pediatric AVM …

Stereotactic Radiosurgery for Pediatric Brain Arteriovenous Malformations: Long-Term Outcomes

CJ Chen, CC Lee, KN Kearns, D Ding… - …, 2019 - journals.lww.com
METHODS: We retrospectively analyzed the International Radiosurgery Research
Foundation pediatric AVM database from 1987 to 2018. AVM obliteration, post-SRS
hemorrhage, cyst formation, and tumor formation were assessed. Cumulative probabilities,
adjusted for competing risk of death, were calculated. RESULTS: The study cohort
comprised 539 pediatric AVM patients (mean follow-up: 85.8 mo). AVM obliteration was
observed in 64.3% of patients, with cumulative probabilities of 63.6%(95% CI: 58.8 …
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