Systemic and ovarian inflammation in women with polycystic ovary syndrome

Y Zhai, Y Pang - Journal of Reproductive Immunology, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is a common endocrine/reproductive/metabolic disorder.
The etiology of PCOS is complex and has been linked to low-grade chronic inflammation.
Local inflammation of the ovary affects ovulation and induces or aggravates systemic
inflammation. PCOS patients demonstrated significantly higher concentrations of circulating
inflammatory cells, such as lymphocytes, neutrophils, eosinophilic granulocytes, monocytes
and Th17 cells than women without PCOS, while the percentage of Treg cells was lower …
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