Background Patients with Parkinson's disease have substantially impaired balance, leading
to diminished functional ability and an increased risk of falling. Although exercise is routinely
encouraged by health care providers, few programs have been proven effective. Methods
We conducted a randomized, controlled trial to determine whether a tailored tai chi program
could improve postural control in patients with idiopathic Parkinson's disease. We randomly
assigned 195 patients with stage 1 to 4 disease on the Hoehn and Yahr staging scale …

In this study, the authors recruited participants from seven hospitals in England who were 16-
50 years of age with pregnancies of 12-24 weeks' gestation and who smoked 5 or more
cigarettes per day. Participants received behavioural cessation support and were randomly
assigned to 8 weeks of treatment with active nicotine patches (15 mg per 16 hours) or
matched placebo patches. The primary outcome was abstinence from the date of smoking
cessation until delivery, as validated by measurement of exhaled carbon monoxide or …