The cost of drug development: a systematic review

S Morgan, P Grootendorst, J Lexchin, C Cunningham… - Health policy, 2011 - Elsevier
OBJECTIVES: We aimed to systematically review and assess published estimates of the
cost of developing new drugs. METHODS: We sought English language research articles
containing original estimates of the cost of drug development that were published from 1980
to 2009, inclusive. We searched seven databases and used citation tracing and expert
referral to identify studies. We abstracted qualifying studies for information about methods,
data sources, study samples, and key results. RESULTS: Thirteen articles were found to …
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