The effect of ß-blockers on mental performance on older hypertensive patients
FM Gengo, SC Fagan, A de Padova… - Archives of Internal …, 1988 - jamanetwork.com
• This double-blind, three-way crossover study measured the influence of β-blocker
treatment on drowsiness and mental test performance in older hypertensive patients and
determined if lipophilicity was a determinant of these effects. Twenty-seven hypertensive
patients (mean age, 63±3 years) were studied. Patients received two weeks each of daily
treatment with placebo, 100 mg of atenolol, or 150 mg of metoprolol tartrate and were
evaluated on the 14th day of each treatment period, after which their next treatment period …
treatment on drowsiness and mental test performance in older hypertensive patients and
determined if lipophilicity was a determinant of these effects. Twenty-seven hypertensive
patients (mean age, 63±3 years) were studied. Patients received two weeks each of daily
treatment with placebo, 100 mg of atenolol, or 150 mg of metoprolol tartrate and were
evaluated on the 14th day of each treatment period, after which their next treatment period …
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