Where did SARS-CoV-2 come from?

T Leitner, S Kumar - Molecular biology and evolution, 2020 - academic.oup.com
… , their genetic dissimilarity to SARS-CoV-2 is so high that they … , it was suggested that
SARS-CoV-2 might have evolved in a … The hunt for the zoonotic origin of SARS-CoV-2 continues. …

Evolutionary history, potential intermediate animal host, and cross‐species analyses of SARSCoV2

X Li, J Zai, Q Zhao, Q Nie, Y Li, BT Foley… - Journal of medical …, 2020 - Wiley Online Library
… respiratory syndrome coronavirus 2 (SARS-CoV-2) in China, … animal host of the SARS-CoV-2
virus, we reanalyzed virome … ancestor and evolutionary rate of SARS-CoV-2, which ranged …

Understanding evolution of SARSCoV2: a perspective from analysis of genetic diversity of RdRp gene

SM Kasibhatla, M Kinikar, S Limaye… - Journal of medical …, 2020 - Wiley Online Library
… that SARS-CoV-2 is a homogeneous population. SARS-CoV-2 appears to have evolved
a common ancestor from which Pangolin-CoVs have also evolved. The admixed Bat-CoV sub-…

Synonymous mutations and the molecular evolution of SARS-Cov-2 origins

H Wang, L Pipes, R Nielsen - Virus evolution, 2021 - academic.oup.com
… We focus further on studying the synonymous evolution of SARS-CoV-2, and analyzing
Wuhan-Hu-1 as the human nCoV19 reference strain (Wu et al. 2020) along with the four viral …

[HTML][HTML] One year of SARS-CoV-2: how much has the virus changed?

S Vilar, DG Isom - Biology, 2021 - mdpi.com
… high adaptive evolution, we expect that SARS-CoV-2 presents … We analyzed the evolution
of the SARS-CoV-2 virus over a … in the mutational evolution of SARS-CoV-2. We observed two …

[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
… protein evolution and mutation supporting adaptation to the human host and provide an
overview of current vaccine approaches and therapeutic strategies targeting SARS-CoV-2 entry …

[PDF][PDF] Exploring the natural origins of SARS-CoV-2 in the light of recombination

S Lytras, J Hughes, D Martin… - … and Evolution, 2022 - academic.oup.com
… best estimates of SARS-CoV-2 and related sarbecoviruses true evolutionary history) with the
… understanding of the recent evolutionary histories of SARS-CoV2’s closest known relatives …

[HTML][HTML] The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology

BB Oude Munnink, N Worp, DF Nieuwenhuijse… - Nature medicine, 2021 - nature.com
… to the most recent common ancestor of SARS-CoV-2 and the related pangolin … development
of specific SARS-CoV-2 whole-genome sequencing protocols 8 and the rapid development

Mutations strengthened SARS-CoV-2 infectivity

J Chen, R Wang, M Wang, GW Wei - Journal of molecular biology, 2020 - Elsevier
… These challenges are deteriorated by the continuous evolution of SARS-CoV-2 due to its
over 10,000 single nucleotide polymorphisms variants in various distinct clusters [5]. In the …

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

H Tegally, JE San, M Cotten, M Moir, B Tegomoh… - Science, 2022 - science.org
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing
in Africa over the past year has led to a major increase in the number of sequences that have …