The neuroprotective effects and transdifferentiation of astrocytes into dopaminergic neurons of Ginkgolide K on Parkinson'disease mice
Q Miao, Z Chai, LJ Song, Q Wang, GB Song… - Journal of …, 2022 - Elsevier
Parkinson's disease (PD) is a chronic and progressive movement disorder caused by the
selective loss of midbrain dopaminergic neurons of unknown etiology. Up to now, although
there is a great development on treatments of PD, cures with neuroprotective or nerve
regenerative effects are underway for PD patients. Here we reported neuroprotective effects
of Ginkgolide K (GK) when mice were upon acute MPTP exposure, in which GK ameliorated
the gait dysfunction and dopaminergic neuron loss. GK exhibits its ability in …
selective loss of midbrain dopaminergic neurons of unknown etiology. Up to now, although
there is a great development on treatments of PD, cures with neuroprotective or nerve
regenerative effects are underway for PD patients. Here we reported neuroprotective effects
of Ginkgolide K (GK) when mice were upon acute MPTP exposure, in which GK ameliorated
the gait dysfunction and dopaminergic neuron loss. GK exhibits its ability in …
