While inflammation may not be the cause of disease, it is well known that it contributes to
disease pathogenesis across a multitude of peripheral and central nervous system
disorders. Chronic and overactive inflammation due to an effector T-cell-mediated aberrant
immune response ultimately leads to tissue damage and neuronal cell death. To counteract
peripheral and neuroinflammatory responses, research is being focused on regulatory T cell
enhancement as a therapeutic target. Regulatory T cells are an immunosuppressive …

While inflammation may not be the cause of disease, it is well known that it contributes to
disease pathogenesis across a multitude of peripheral and central nervous system
disorders. Chronic and overactive inflammation due to an effector T cell-mediated aberrant
immune response ultimately leads to tissue damage and neuronal cell death. To counteract
peripheral and neuroinflammatory responses, research is being focused on regulatory T cell
enhancement as a therapeutic target. Regulatory T cells are an immunosuppressive …