The role of cerebrovascular disease in amyloid deposition

Y Noh, SW Seo, S Jeon, JM Lee, JS Kim… - Journal of …, 2016 - content.iospress.com
Y Noh, SW Seo, S Jeon, JM Lee, JS Kim, JH Lee, JH Kim, GH Kim, BS Ye, H Cho, HJ Kim…
Journal of Alzheimer's Disease, 2016content.iospress.com
… Objective: We investigated topographical differences in amyloid burden between SVCI
and Alzheimer’s disease type cognitive impairment (ADCI) using [ 11 C] Pittsburgh
compound B (PiB) positron emission tomography (PET). The purpose of this study was to
investigate the role of cerebrovascular disease (CVD) in amyloid deposition. … Therefore,
our finding that the topography of amyloid deposition differed between SVCI and ADCI
suggests that the CVD may have additional effects on amyloid deposition in SVCI. This may …
Abstract
Background: Some patients clinically diagnosed with subcortical vascular cognitive impairment (SVCI) have co-morbidity with AD pathology.
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