The fourth industrial revolution presents an upspring opportunity for the African continent to adopt technologies such as artificial intelligence, big data, internet-enabled industrial platforms, 3D printing, robotics, nanotechnology, and blockchains. This is more so because the past three industrial revolutions saw the African continent being left out of its opportunities despite its affluent population and natural resources. Africa stands to benefit from industrial development, digitalization, and greater integration, which would result in more excellent opportunities for the growing youthful populations. However, for the digital transformation strategy and other key industry 4.0 opportunities to be successful, reliable infrastructure, affordable and stable electricity, and greater awareness are critical and imperative. This review examines the possible energy options that the continent of Africa can explore and implement for the successful deployment of Industry 4.0. The impact, difficulties, and opportunities of the fourth industrial revolution technologies on African development are discussed. Also discussed are various forms of renewable energy options based on Africa’s geographic location. This review will assist researchers and policymakers in implementing Industry 4.0 in Africa.