Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey
M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
… on the pathophysiological implications of glycosylation. Fortunately, cutting-edge …
cancer-related glycosylation. Thus, glycans as well as aberrantly glycosylated protein-based cancer …
cancer-related glycosylation. Thus, glycans as well as aberrantly glycosylated protein-based cancer …
[HTML][HTML] Hallmarks of glycosylation in cancer
J Munkley, DJ Elliott - Oncotarget, 2016 - ncbi.nlm.nih.gov
… Aberrant glycosylation is often cited as a ‘hallmark of cancer’ … than aberrant glycosylation
being itself a hallmark of cancer, … that glycans play a role in every recognised cancer hallmark. …
being itself a hallmark of cancer, … that glycans play a role in every recognised cancer hallmark. …
Aberrant glycosylation in cancer: a novel molecular mechanism controlling metastasis
Glycosylation alterations are involved in several steps of human cancer pathogenesis. In this
issue of Cancer Cell, Agrawal et al. identified the glycosyltransferase FUT8 as a previously …
issue of Cancer Cell, Agrawal et al. identified the glycosyltransferase FUT8 as a previously …
Aberrant glycosylation associated with enzymes as cancer biomarkers
DL Meany, DW Chan - Clinical proteomics, 2011 - Springer
… of cancer biomarker discovery using aberrant glycosylation in three areas. First, changes in
glycosylation machinery such as glycosyltransferases/glycosidases could be used as cancer …
glycosylation machinery such as glycosyltransferases/glycosidases could be used as cancer …
Aberrant glycosylation as biomarker for cancer: focus on CD43
FM Tuccillo, A de Laurentiis, C Palmieri… - BioMed research …, 2014 - Wiley Online Library
… cancer biomarkers. In particular, we will focus on the aberrant CD43 glycosylation as cancer
… to exploit the UN1 monoclonal antibody (UN1 mAb) to identify aberrant CD43 glycoforms. …
… to exploit the UN1 monoclonal antibody (UN1 mAb) to identify aberrant CD43 glycoforms. …
Aberrant protein glycosylation in cancer: implications in targeted therapy
… Furthermore, such aberrant glycan structures play key roles in the acquisition of molecular
… anti-cancer targeted agents. In this review, we highlight the impact of glycosylation in cancer …
… anti-cancer targeted agents. In this review, we highlight the impact of glycosylation in cancer …
Epigenetic bases of aberrant glycosylation in cancer
F Dall'Olio, M Trinchera - International journal of molecular sciences, 2017 - mdpi.com
… in cancer. We see how different epigenetic mechanisms converge to regulate specific pathways
of cancer-… We also summarize the case of O-linked GlcNAc, in which glycosylation is not …
of cancer-… We also summarize the case of O-linked GlcNAc, in which glycosylation is not …
Altered glycosylation in cancer: A promising target for biomarkers and therapeutics
… cancer … glycosylation machinery is associated with cancer progression and metastasis. We
also provide insights into the influence of aberrant glycosylation in the development of cancer …
also provide insights into the influence of aberrant glycosylation in the development of cancer …
Glycosylation: a hallmark of cancer?
BN Vajaria, PS Patel - Glycoconjugate journal, 2017 - Springer
… remarkable progress in cancer research, … Aberrant glycosylation interferes with regulation
of cell adhesion, migration and proliferation. Glycosylation may represent a hallmark of cancer, …
of cell adhesion, migration and proliferation. Glycosylation may represent a hallmark of cancer, …
Glycosylation in cancer: mechanisms and clinical implications
… of cancer cells. The most-widely occurring changes in glycosylation associated with cancer
… Aberrant glycosylation in cancer frequently involves an increase in sialyl Lewis x (SLe x ) …
… Aberrant glycosylation in cancer frequently involves an increase in sialyl Lewis x (SLe x ) …
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