Interleukin-6: A promising cytokine to support liver regeneration and adaptive immunity in liver pathologies

S Naseem, T Hussain, S Manzoor - Cytokine & growth factor reviews, 2018 - Elsevier
adaptive immuneliver regeneration and in supporting effector immune functions and
suggests that these functions of IL-6 can be exploited in treatment strategies for liver pathologies. …

Adaptive immunity: an emerging player in the progression of NAFLD

S Sutti, E Albano - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
… We also highlight the mechanisms affecting liver immune tolerance in the setting of
steatohepatitis that favour lymphocyte activation. Finally, we analyse emerging evidence concerning …

Liver-mediated adaptive immune tolerance

M Zheng, Z Tian - Frontiers in immunology, 2019 - frontiersin.org
… However, optimal protective adaptive immune responses … immune cells in the host. In this
review, we focus on the mechanisms involved in hepatic adaptive immune tolerance, the liver

Adaptive immunity in the liver

JD Gorham - Liver Immunology: Principles and Practice, 2007 - Springer
… CD4 + T cells can differentiate into several types of effector cells that produce specific
cytokines implicated in specific liver pathologies. These subsets include Th1, Th2, T-reg, and the …

Immunopathology of chronic hepatitis B infection: role of innate and adaptive immune response in disease progression

A Khanam, JV Chua, S Kottilil - International Journal of Molecular …, 2021 - mdpi.com
… innate and adaptive immune cells play crucial roles in controlling hepatitis B virus (HBV)
infection, they are also accountable for inflammation and subsequently cause liver pathologies. …

Liver immunology and its role in inflammation and homeostasis

MW Robinson, C Harmon, C O'Farrelly - Cellular & molecular …, 2016 - nature.com
… , are key drivers of the liver pathology associated with chronic infection, autoimmunity and …
innate and adaptive immune responses in the liver. The repertoire of liver innate lymphocytes …

Liver immunobiology

GA Parker, CA Picut - Toxicologic Pathology, 2005 - journals.sagepub.com
… The liver has a number of important functions in innate and adaptive immunity. … cells are
known to influence adaptive immune processes in the liver. These effects are mediated primarily …

[HTML][HTML] Liver immunity, autoimmunity, and inborn errors of immunity

YE Parlar, SN Ayar, D Cagdas… - World Journal of …, 2023 - ncbi.nlm.nih.gov
immune processes and how liver immunity functions during normal liver homeostasis and liver
pathologies, … which is driven by pathological responses of the adaptive immune system[4]. …

[PDF][PDF] Immune tolerance in liver disease

IN Crispe - Hepatology, 2014 - Wiley Online Library
… fragments that acts through TGF-b1 and IL-10 to induce PD-L1 may be a mechanism to
promote both reduced liver inflammation and tolerance of adaptive immune mechanisms (Fig. 1). …

Inflammatory processes in the liver: divergent roles in homeostasis and pathology

O Ahmed, MW Robinson, C O'Farrelly - Cellular & Molecular …, 2021 - nature.com
… In addition, both human and murine models have been used to study adaptive immune
responses and T-cell recruitment in inflammatory hypoxia, and selective FoxP3 induction and …