Adenosine A2B receptors

I Feoktistov, I Biaggioni - Pharmacological reviews, 1997 - ASPET
… of adenosine receptors, but our knowledge of A 2B receptors lags behind that of other receptor
… Perhaps because of their lower affinity for adenosine compared with other receptors, it is …

The adenosine a2b receptor: its role in inflammation

J Ham, DA Rees - … Metabolic & Immune Disorders-Drug Targets …, 2008 - ingentaconnect.com
… homology between the human A2b and A1 and A2a receptors [61]. As expected the membrane
structure of the A2b receptor is typical of many G protein coupled receptors as there are …

Pharmacology of adenosine A2A receptors

E Ongini, BB Fredholm - Trends in pharmacological sciences, 1996 - cell.com
Adenosine interacts with at least four different G proteincoupled receptors, namely adenosine
A;, A:A, A2B and A~ receptors~, all of which have been cloned from several mammalian …

Potential therapeutic relevance of adenosine A2B and A2A receptors in the central nervous system

P Popoli, R Pepponi - … (Formerly Current Drug Targets-CNS & …, 2012 - ingentaconnect.com
… only under pathological conditions (when adenosine levels raise up to micromolar … for
A2B receptors would allow exploration of such an hypothesis. Since adenosine A2A receptors

A2B Adenosine Receptor and Cancer

ZG Gao, KA Jacobson - International journal of molecular sciences, 2019 - mdpi.com
… mainly via the degradation of adenosine 5′-triphosphate (… Adenosine and ATP acting at
different classes of receptors … 1 receptor (P2Y 1 R) subtype [1,2], whereas adenosine induces …

Adenosine A2B receptors as therapeutic targets

I Feoktistov, JN Wells, I Biaggioni - Drug development research, 1998 - Wiley Online Library
… Four subtypes of adenosine receptors have been cloned: A1, A2A, A2B, and A3. Significant
adenosine receptors, but our knowledge of A2B receptors lags behind that of other receptor

Differential effects of adenosine A2a and A2b receptors on cardiac contractility

PC Chandrasekera, VJ McIntosh… - American Journal of …, 2010 - journals.physiology.org
adenosine is an autocoid that exerts several well-known receptor-mediated effects in the
heart via four different adenosine receptors (ARs): A 1 AR, A 2a AR, A 2b AR, and A 3 AR. A 1 …

Medicinal chemistry and pharmacology of A2B adenosine receptors

R Volpini, S Costanzi, S Vittori… - Current topics in …, 2003 - ingentaconnect.com
… Through A2B receptors adenosine seems to cause mast cells … Hence, A2B adenosine
receptor agonists could be useful in the … A future therapeutic purpose for adenosine A2B receptor

Pharmacological characterization of adenosine A2B receptors: studies in human mast cells co-expressing A2A and A2B adenosine receptor subtypes

I Feoktistov, I Biaggioni - Biochemical pharmacology, 1998 - Elsevier
… We demonstrated that A 2B receptors can be selectively activated … 2B receptors. Using the
approaches developed in this study, we determined that A 2B , and not A 2A or A 3 , receptors

A2B adenosine receptors in immunity and inflammation

G Haskó, B Csóka, ZH Németh, ES Vizi, P Pacher - Trends in immunology, 2009 - cell.com
… The A2B adenosine receptor protects against inflammation and excessive vascular …
signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. …