BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… BRAF mutation occurs in papillary thyroid cancer (PTC) with a prevalence ranging from 29
to 83% (4–19). The T1799A BRAF mutation … aggressive when BRAF mutation was present. …
to 83% (4–19). The T1799A BRAF mutation … aggressive when BRAF mutation was present. …
… prevalence of BRAF mutation in a Brazilian cohort of patients with sporadic papillary thyroid carcinomas Correlation with more aggressive phenotype and decreased …
G Oler, JM Cerutti - … Journal of the American Cancer Society, 2009 - Wiley Online Library
… Although we have previously investigated BRAF mutation in 13 matched primary tumor and
… the BRAF mutation was associated with prognostic factors such as age, sex, tumor size, …
… the BRAF mutation was associated with prognostic factors such as age, sex, tumor size, …
BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas
MN Nikiforova, ET Kimura, M Gandhi… - The Journal of …, 2003 - academic.oup.com
… carcinomas, the most aggressive types of thyroid neoplasm. In addition, it is … thyroid tumors
and benign nodules for BRAF mutation, report a novel method of screening for the mutation, …
and benign nodules for BRAF mutation, report a novel method of screening for the mutation, …
BRAF V600E does not predict aggressive features of pediatric papillary thyroid carcinoma
DJ Givens, LO Buchmann, AM Agarwal… - The …, 2014 - Wiley Online Library
… the prevalence of the BRAF V600E mutation in pediatric papillary thyroid carcinoma (PTC) …
, the cumulative presence of BRAF V600E in pediatric thyroid cancer was 28.4% (Table 3). …
, the cumulative presence of BRAF V600E in pediatric thyroid cancer was 28.4% (Table 3). …
[HTML][HTML] Papillary thyroid cancer—Aggressive variants and impact on management: A narrative review
A Coca-Pelaz, JP Shah, JC Hernandez-Prera… - Advances in …, 2020 - Springer
… good survival despite the aggressive clinical presentation. BRAF mutation has also been …
However, the reported rates of BRAF mutation vary significantly between studies. Lee et al. […
However, the reported rates of BRAF mutation vary significantly between studies. Lee et al. […
[HTML][HTML] BRAF V600E mutation correlates with aggressive clinico-pathological features but does not influence tumor recurrence in papillary thyroid carcinoma—10 …
… the aggressive tumor behavior of BRAF+ PTC. The question arises whether BRAF mutation
plays a role as a prognostic marker, and how we should deal with BRAF+ tumors. This issue …
plays a role as a prognostic marker, and how we should deal with BRAF+ tumors. This issue …
… of BRAF gene mutation in thyroid tumors: Significant association with papillary tumors and extra thyroidal extension indicating its role as a biomarker of aggressive …
… In the current study, 95 specimens of thyroid tumors were subjected to BRAF mutation
analysis. The clinicopathological findings of all the specimen is presented in Table-1. The median …
analysis. The clinicopathological findings of all the specimen is presented in Table-1. The median …
[HTML][HTML] Genetic profiles of aggressive variants of papillary thyroid carcinomas
M Jin, DE Song, J Ahn, E Song, YM Lee, TY Sung… - Cancers, 2021 - mdpi.com
… In PTC, TERT promoter mutation was more frequent in BRAF mutated tumors [31], which is
… promoter mutations, five (83.3%) had a coexisting BRAF mutation. TP53, a tumor suppressor …
… promoter mutations, five (83.3%) had a coexisting BRAF mutation. TP53, a tumor suppressor …
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer
M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
… Many studies have shown an association of the BRAF V600E mutation with aggressive
clinicopathological characteristics of PTC, including LNM, extrathyroidal invasion, loss of …
clinicopathological characteristics of PTC, including LNM, extrathyroidal invasion, loss of …
BRAFV600E Mutation and Outcome of Patients with Papillary Thyroid Carcinoma: A 15-Year Median Follow-Up Study
R Elisei, C Ugolini, D Viola, C Lupi… - The Journal of …, 2008 - academic.oup.com
… Recently, the relationship between the BRAF V600E mutation and a higher aggressiveness
of PTC has been attributed to a significantly higher expression of vascular endothelial …
of PTC has been attributed to a significantly higher expression of vascular endothelial …