BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
BRAF mutation occurs in papillary thyroid cancer (PTC) with a prevalence ranging from 29
to 83% (4–19). The T1799A BRAF mutationaggressive when BRAF mutation was present. …

… prevalence of BRAF mutation in a Brazilian cohort of patients with sporadic papillary thyroid carcinomas Correlation with more aggressive phenotype and decreased …

G Oler, JM Cerutti - … Journal of the American Cancer Society, 2009 - Wiley Online Library
… Although we have previously investigated BRAF mutation in 13 matched primary tumor and
… the BRAF mutation was associated with prognostic factors such as age, sex, tumor size, …

BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas

MN Nikiforova, ET Kimura, M Gandhi… - The Journal of …, 2003 - academic.oup.com
carcinomas, the most aggressive types of thyroid neoplasm. In addition, it is … thyroid tumors
and benign nodules for BRAF mutation, report a novel method of screening for the mutation, …

BRAF V600E does not predict aggressive features of pediatric papillary thyroid carcinoma

DJ Givens, LO Buchmann, AM Agarwal… - The …, 2014 - Wiley Online Library
… the prevalence of the BRAF V600E mutation in pediatric papillary thyroid carcinoma (PTC) …
, the cumulative presence of BRAF V600E in pediatric thyroid cancer was 28.4% (Table 3). …

[HTML][HTML] Papillary thyroid cancerAggressive variants and impact on management: A narrative review

A Coca-Pelaz, JP Shah, JC Hernandez-Prera… - Advances in …, 2020 - Springer
… good survival despite the aggressive clinical presentation. BRAF mutation has also been …
However, the reported rates of BRAF mutation vary significantly between studies. Lee et al. […

[HTML][HTML] BRAF V600E mutation correlates with aggressive clinico-pathological features but does not influence tumor recurrence in papillary thyroid carcinoma—10 …

N Tabriz, J Grone, V Uslar, A Tannapfel, D Weyhe - Gland Surgery, 2020 - ncbi.nlm.nih.gov
… the aggressive tumor behavior of BRAF+ PTC. The question arises whether BRAF mutation
plays a role as a prognostic marker, and how we should deal with BRAF+ tumors. This issue …

… of BRAF gene mutation in thyroid tumors: Significant association with papillary tumors and extra thyroidal extension indicating its role as a biomarker of aggressive …

F Ahmad, R Nathani, J Venkat, A Bharda… - … and molecular pathology, 2018 - Elsevier
… In the current study, 95 specimens of thyroid tumors were subjected to BRAF mutation
analysis. The clinicopathological findings of all the specimen is presented in Table-1. The median …

[HTML][HTML] Genetic profiles of aggressive variants of papillary thyroid carcinomas

M Jin, DE Song, J Ahn, E Song, YM Lee, TY Sung… - Cancers, 2021 - mdpi.com
… In PTC, TERT promoter mutation was more frequent in BRAF mutated tumors [31], which is
… promoter mutations, five (83.3%) had a coexisting BRAF mutation. TP53, a tumor suppressor …

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
… Many studies have shown an association of the BRAF V600E mutation with aggressive
clinicopathological characteristics of PTC, including LNM, extrathyroidal invasion, loss of …

BRAFV600E Mutation and Outcome of Patients with Papillary Thyroid Carcinoma: A 15-Year Median Follow-Up Study

R Elisei, C Ugolini, D Viola, C Lupi… - The Journal of …, 2008 - academic.oup.com
… Recently, the relationship between the BRAF V600E mutation and a higher aggressiveness
of PTC has been attributed to a significantly higher expression of vascular endothelial …