… Furthermore, it has been demonstrated that selective BRAF V600E inhibitor (… BRAF V600E
thyroid cancer cells and tumor aggressiveness in preclinical models of human thyroid cancer.…

… follicular adenomas, well-differentiated papillary and follicular carcinomas, and aggressive
anaplastic … Here, we report that BRAF mutation at V599E occurred in 21 of 56 papillary …

… However, the association of BRAFV600E with aggressive clinical behaviors of papillary
thyroid microcarcinoma (PTMC) has not been firmly established in individual studies. We …

… aggressive PTMCs may arise in a subset of patients with BRAF V600E mutation and tumors
… BRAF mutations may occur in papillary thyroid carcinoma and also have been reported in …

… cancer (27–32). Intriguingly, the BRAF mutation in thyroid cancer occurs exclusively in PTC
… are fundamentally associated with the increased progression and aggressiveness of PTC. …

… could be useful to identify within patients with intrathyroid ultrasound-N0 PTC those who
require more aggressive treatment, by central neck node dissection (CLND) or subsequent …

… The aim of this study was to investigate the frequency of the BRAF mutation in papillary
thyroid carcinoma (PTC) of Koreans through direct DNA sequencing of the polymerase chain …

… -positive microPTC patients more aggressively; hence, BRAF mutation-negative microPTCs
… To verify whether BRAF mutations could help to predict more aggressive biological behavior …

… Recently, the association of the BRAFV600E mutation with aggressive disease was also
addressed in a metaanalysis of 1168 patients from 12 studies. This showed an association of …

… of Hashimoto's thyroiditis and BRAF V600E mutation status on aggressiveness in papillary …
outcome in a BRAF V600E-prevalent papillary thyroid cancer population Thyroid 2014 24 689…