Synthesis of amphiphilic Janus dendrimer and its application in improvement of hydrophobic drugs solubility in aqueous media
F Najafi, M Salami-Kalajahi… - European Polymer …, 2020 - Elsevier
… dendrimers in drug delivery including solubility improvement of hydrophobic drugs, Janus
dendrimers are used to improve solubility … different generations of Janus dendrimers. Since the …
dendrimers are used to improve solubility … different generations of Janus dendrimers. Since the …
High-generation amphiphilic Janus-dendrimers as stabilizing agents for drug suspensions
M Selin, S Nummelin, J Deleu, J Ropponen… - …, 2018 - ACS Publications
… to stabilize drug suspensions of the poorly water-soluble drugs … by which amphiphilic JDs
stabilize pharmaceutical drug … adsorption kinetics of the JDs to drug crystals in suspension. …
stabilize pharmaceutical drug … adsorption kinetics of the JDs to drug crystals in suspension. …
An emerging class of amphiphilic dendrimers for pharmaceutical and biomedical applications: Janus amphiphilic dendrimers
DR Sikwal, RS Kalhapure, T Govender - European Journal of …, 2017 - Elsevier
… These dendrimers were capable of carrying multiple drug molecules and targeting the bone
… solubility compared to the native naproxen. This enhanced bone-affinity and solubility can …
… solubility compared to the native naproxen. This enhanced bone-affinity and solubility can …
Design and synthesis of novel amphiphilic Janus dendrimers for bone-targeted drug delivery
J Pan, M Wen, D Yin, B Jiang, D He, L Guo - Tetrahedron, 2012 - Elsevier
… a range of amphiphilic Janus dendrimers, which consisted of … solubility data indicated
that amphiphilic Janus dendrimer is a favorable approach to deliver poor water-soluble drugs…
that amphiphilic Janus dendrimer is a favorable approach to deliver poor water-soluble drugs…
[HTML][HTML] Properties and bioapplications of amphiphilic janus dendrimers: A Review
A Căta, IMC Ienașcu, MN Ştefănuț, D Roșu, OR Pop - Pharmaceutics, 2023 - mdpi.com
… water-soluble drug molecules. Amphiphilic Janus dendrimers can be adsorbed onto drug …
offering a versatile platform for general use as stabilizing agents for drug suspensions [106]. …
offering a versatile platform for general use as stabilizing agents for drug suspensions [106]. …
Janus-type dendrimers: Synthesis, properties, and applications
F Najafi, M Salami-Kalajahi… - Journal of Molecular …, 2022 - Elsevier
… Janus dendrimers have enhanced solubility, electrochemical … To improve the solubility of
hydrophobic drugs in water, … Two of the amphiphilic Janus dendrimers included galactose …
hydrophobic drugs in water, … Two of the amphiphilic Janus dendrimers included galactose …
“Single–single” amphiphilic janus dendrimers self-assemble into uniform dendrimersomes with predictable size
S Zhang, HJ Sun, AD Hughes, B Draghici, J Lejnieks… - ACS …, 2014 - ACS Publications
… All Janus dendrimers are soluble in ethanol at concentrations ranging from 10 to 40 mg/mL.
This concentration is in the range of the stock solution required for the self-assembly of …
This concentration is in the range of the stock solution required for the self-assembly of …
[HTML][HTML] Vesicles from amphiphilic dumbbells and janus dendrimers: Bioinspired self-assembled structures for biomedical applications
S Taabache, A Bertin - Polymers, 2017 - mdpi.com
… Vesicular structures as drug delivery systems (DDS) might help overcoming the
limitations of free drugs, such as poor water-solubility, severe side-effects due to a non-selective …
limitations of free drugs, such as poor water-solubility, severe side-effects due to a non-selective …
Self-assembling amphiphilic Janus dendrimers: mesomorphic properties and aggregation in water
E Fedeli, A Lancelot, JL Serrano, P Calvo… - New Journal of …, 2015 - pubs.rsc.org
… amphiphilic Janus dendrimers derived from 2,2-bis(hydroxymethyl)propionic acid (bis-MPA).
Bis-MPA based dendrimers exhibit excellent aqueous solubility … to build drug carriers 27,28 …
Bis-MPA based dendrimers exhibit excellent aqueous solubility … to build drug carriers 27,28 …
Janus Dendrimers as Nanocarriers of Ibuprofen, Chlorambucil and their Anticancer Activity
LD Pedro-Hernández… - Pharmaceutical …, 2024 - ingentaconnect.com
… amphiphilic copolymers, their dendritic counterparts, Janus … drug) on the other side, but its
biological activity was not determined [29]… Herein, we report the synthesis of Janus dendrimers …
biological activity was not determined [29]… Herein, we report the synthesis of Janus dendrimers …
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