Targeted and equally distributed delivery of mrna to organs with pentaerythritol-based one-component ionizable amphiphilic janus dendrimers

J Lu, EN Atochina-Vasserman, DS Maurya… - Journal of the …, 2023 - ACS Publications
… One-component multifunctional sequence-defined ionizable amphiphilic Janus dendrimer
(IAJD) … They were inspired by amphiphilic Janus dendrimers and glycodendrimers. IAJDs …

Dual-targeting janus dendrimer based peptides for bone cancer: Synthesis and preliminary biological evaluation

B Jiang, J Zhao, Y Li, D He, J Pan… - Letters in Organic …, 2013 - ingentaconnect.com
… Design and synthesis of novel amphiphilic Janus dendrimers for bonetargeted drug
delivery. Tetrahedron, 2012, 68, 2943-2949. [30] Gillies, ER; Frechet, JMJ Designing …

Multifunctional triazolylferrocenyl Janus dendron: Nanoparticle stabilizer, smart drug carrier and supramolecular nanoreactor

L Zhao, Q Ling, X Liu, C Hang, Q Zhao… - Applied …, 2018 - Wiley Online Library
… Owing to their unique broken symmetry, amphiphilic Janus dendrimers and dendons … As
shown in Figure 1, a new water-soluble catalyst, 7-Cu I , was prepared by amphiphilic dendron …

Dual drug delivery and sequential release by amphiphilic Janus nanoparticles for liver cancer theranostics

L Zhang, M Zhang, L Zhou, Q Han, X Chen, S Li, L Li… - Biomaterials, 2018 - Elsevier
… of inorganic Janus NP (JNP), they can host drugs with different solubility in their distinct … of
individual drugs compared to the conventional NPs normally with circumscribed drug release …

Janus nanoparticles: materials, preparation and recent advances in drug delivery

LTC Tran, S Lesieur, V Faivre - Expert opinion on drug delivery, 2014 - Taylor & Francis
… As the other amphiphilic molecules act, Janus dendrimers also produce a plethora of self-…
that have widely disparate solubility or charge, dual-phase release kinetics, drug targeting and …

Janus-dendrimer-mediated formation of crystalline virus assemblies

J Mikkila, H Rosilo, S Nummelin, J Seitsonen… - ACS Macro …, 2013 - ACS Publications
… In this work, four new amphiphilic dendrimers were synthesized (Figure 1) by combining …
solubility of the nonpolar parts of the amphiphilic dendrimers, which may drive the dendrimers to …

Synthesis and Characterization of PAMAM-Fatty Acid “Janus-type” Dendritic Hybrids for Biomedical Applications

AG Barker - 2020 - egrove.olemiss.edu
Janus dendrimers are amphiphilic macromolecules that have … , solubility, inefficient drug
loading, and uncontrolled drug … class of dendrimers emerged called Janus dendrimers (JDs). …

Preparation of Janus nanoparticles and its application in drug delivery

S Khoee, A Nouri - Design and development of new nanocarriers, 2018 - Elsevier
… , amphiphilic Janus nanoparticles can be served to deliver two types of drugs with different
solubility. … In another example, amphiphilic Janus dendrimers as bone-targeting dendritic …

[HTML][HTML] … to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant …

J Lu, EN Atochina-Vasserman, DS Maurya, MI Shalihin… - Pharmaceutics, 2023 - mdpi.com
… containing long alkyl groups and increase the solubility of the IAJD in ethanol. The decreased
rate of crystallization and increased solubility of IAJD were indeed accomplished using …

[HTML][HTML] Dendrimers: exploring their wide structural variety and applications

M Pérez-Ferreiro, A M. Abelairas, A Criado, IJ Gómez… - Polymers, 2023 - mdpi.com
… such as solubility, polarity, or the ability of the dendrimer to … drugs that have poor solubility
in water [20]. Moreover, PPI … library of 107 amphiphilic Janus dendrimers by combining two …