Encapsulation of hydrophobic components in dendrimersomes and decoration of their surface with proteins and nucleic acids

P Torre, Q Xiao, I Buzzacchera… - Proceedings of the …, 2019 - National Acad Sciences
… self-assembled from amphiphilic Janus dendrimers, called … Coassembly of amphiphilic
Janus dendrimers with metal-… of a hydrophobic drug, a basic form of the anthracycline drug

Polyester-Pamam “Janus-Type” Linear-Dendritic Blockopolymers (LDBCS) as Next Generation Biomaterials

I Chandrasiri - 2021 - search.proquest.com
… In particular, amphiphilic diblock copolymers and their self-assemblies have shown … A
feasible and robust synthetic strategy was used to synthesize a library of amphiphilic linear …

Amphiphilic cationic carbosilane–PEG dendrimers: synthesis and applications in gene therapy

J Sánchez-Nieves, P Fransen, D Pulido… - European Journal of …, 2014 - Elsevier
… Although these molecules are highly hydrophobic, water-soluble cationic carbosilane
dendrimers have proved useful as non-viral vectors for gene therapy [32], [33], [34], [35], [36]. Their …

The Constitutional Isomerism of One-Component Ionizable Amphiphilic Janus Dendrimers Orchestrates the Total and Targeted Activities of mRNA Delivery

D Sahoo, EN Atochina-Vasserman… - Journal of the …, 2024 - ACS Publications
… on amphiphilic Janus dendrimers (JDs) (7) and sequence-defined Janus glycodendrimers
(… multifunctional sequence-defined ionizable amphiphilic Janus dendrimer (IAJD) to provide a …

Design, synthesis of Janus dendrons conjugated with ketoprofen and prednisone for human chronic myelogenous therapy

LD Pedro-Hernández, I Hernández-Rioja… - Tetrahedron, 2023 - Elsevier
… The present study shows the synthesis of Janus dendrimersdrug and the other a nonsteroidal
anti-inflammatory drug (… Tris based dendrimers exhibit excellent aqueous solubility and …

[HTML][HTML] pH-sensitive dendrimersomes of hybrid triazine-carbosilane dendritic amphiphiles-smart vehicles for drug delivery

E Apartsin, N Knauer, V Arkhipova, E Pashkina… - Nanomaterials, 2020 - mdpi.com
… building dendrimer scaffolds [25] and for the functionalisation of … soluble or highly toxic
compounds into cells. As a proof-of-concept study, we attempted to encapsulate anti-cancer drugs

Amphiphilic Janus dendrimer-stabilized Au, Ag and Pd nanoparticles for the reduction of 4-nitrophenol and Suzuki-Miyaura cross-coupling reactions

F Liu, X Liu - Colloids and Surfaces A: Physicochemical and …, 2024 - Elsevier
… ], [33], protein delivery [34], drug delivery [35], self-assembly [36], … dropwise into a solution
of amphiphilic Janus dendrimer (9 mL, … to enhance the solubility of PdCl 2 in deionized H 2 O. …

Facile fabrication route of janus gold-mesoporous silica nanocarriers with dual-drug delivery for tumor therapy

Y Xing, Y Zhou, Y Zhang, C Zhang… - ACS Biomaterials …, 2020 - ACS Publications
… is reduced, it is beneficial to decrease the side effects of the drug. Unfortunately, they
have markedly different water solubilities, posing a huge challenge for loading both drugs

Amphiphilic dendritic derivatives as nanocarriers for the targeted delivery of antimalarial drugs

J Movellan, P Urbán, E Moles, JM de la Fuente… - Biomaterials, 2014 - Elsevier
… antimalarials (poor aqueous solubility), (iv) use of orphan drugs never assayed as malaria
… for the amphiphilic systems, we focused our attention on polyester dendrimers based on 2,2-…

[PDF][PDF] Architectural fabrication of multifunctional janus nanostructures for biomedical applications.

K Harini, K Girigoswami, D Ghosh, P Pallavi… - Nanomedicine …, 2022 - researchgate.net
… The solubility of the precursors can be adjusted to control the … that Janus dendrimer is an
efficient carrier of mRNA [62]. … Simultaneous two drugs release form Janus particles prepared …