Mechanistic study on the antibacterial activity of self-assembled poly (aryl ether)-based amphiphilic dendrimers

R Kannan, P Prabakaran, R Basu, C Pindi… - ACS Applied Bio …, 2019 - ACS Publications
… conventional higher generation dendrimers, establishing the … the hydrophobicity of amphiphilic
dendrimers plays a crucial … design strategies of amphiphilic dendrimers as antibacterial …

Dendrimer prodrugs

S da Silva Santos, E Igne Ferreira, J Giarolla - Molecules, 2016 - mdpi.com
… One of the results showed that amphiphilic conjugates were able to self-associate in …
series of molecules in improving drug solubility, since the drug could be encapsulated in micelle …

Chemical structure and surface modification of dendritic nanomaterials tailored for therapeutic and diagnostic applications

J Hye Myung, H Hsu, J Bugno… - Current topics in …, 2017 - ingentaconnect.com
… can be used to improve the bioavailability or solubility of hydrophobic anticancer drugs
that … The amphiphilic Janus dendrimers were synthesized via conjugation of a lactose-decorated …

Nanotechnology in pharmaceutical and biomedical applications: Dendrimers

P SZYMAŃSKI, M Markowicz, E MIKICIUK-OLASIK - Nano, 2011 - World Scientific
… or amphiphilic character) into dendritic structure is based on several different mechanisms.
… 151–153 In the case of ibuprofen, PAMAM dendrimers increase the drug solubility more …

Development of Janus particles as potential drug delivery systems for diabetes treatment and antimicrobial applications

KX Tan, MK Danquah, J Jeevanandam, A Barhoum - Pharmaceutics, 2023 - mdpi.com
Janus particles react similarly to amphiphilic molecules with a … drugs with different water
solubility into biocompatible Janus … This is often associated with the use of dendrimers or di-/tri-…

Amphiphilic dendrimer engineered nanocarrier systems for co-delivery of siRNA and paclitaxel to matrix metalloproteinase-rich tumors for synergistic therapy

X Li, A Sun, Y Liu, W Zhang, N Pang, S Cheng… - NPG Asia …, 2018 - nature.com
… -soluble drug paclitaxel (PTX) 19,20 . However, the previous formulations are designed for
delivery of a single chemotherapeutic drug and … a cationic Amphiphilic Dendrimer Engineered …

The dendrimer paradox–high medical expectations but poor clinical translation

S Svenson - Chemical Society Reviews, 2015 - pubs.rsc.org
… the dendrimer's performance, for example its solubility. On … functionalities for drug conjugation
would allow drug loading … , amphiphilic dendrons and dendrimers (‘Janusdendrimers) …

Experimental and theoretical investigations in stimuli responsive dendrimer-based assemblies

MR Molla, P Rangadurai, GM Pavan, S Thayumanavan - Nanoscale, 2015 - pubs.rsc.org
solubility of the dendrimerdrug conjugates. … -soluble assembly that can non-covalently
sequester hydrophobic guest molecules. We have rendered this facially amphiphilic dendrimer

[PDF][PDF] Amphiphilic dendrimers based on polyester dendrons

S Vohra - 2018 - helda.helsinki.fi
… This hydrophobicity makes the dendrimers suitable for combining with feebly soluble drugs
by hydrophobic interactions. Furthermore, in inner cavities atoms such as nitrogen or oxygen …

Dumbbell-Shaped Janus Dendrimersomes Exhibit Lamellar to Sponge Phase Transitions

S Wilner, Q Xiao, V Percec, T Baumgart - Biophysical Journal, 2018 - cell.com
… Self-assembling amphiphilic Janus dendrimers, composed … to external stimuli, including drug
treatment and heat. We … more permeable to water soluble fluorophores after transitioning to …