Antioxidant response element

AK Jaiswal - Biochemical pharmacology, 1994 - Elsevier
electrophile-responsive element. Proc Nat1 Acad Sci … between two TPA responsive elements
in undifferentiated … like binding sites form the electrophile-responsive element of the murine …

The antioxidant/electrophile response element motif

DE Nerland - Drug metabolism reviews, 2007 - Taylor & Francis
… An essential feature of the stress response initiated by electrophilic species is the nuclear …
known as antioxidant response element (ARE) or electrophile response element (EpRE). …

Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response

YC Kim, Y Yamaguchi, N Kondo, H Masutani, J Yodoi - Oncogene, 2003 - nature.com
… the antioxidant responsive element (ARE). We showed here that tert-butylhydroquinone (tBHQ),
an electrophile … transduction through the ARE in electrophile-induced stress responses. …

Functional antioxidant responsive elements

WW Wasserman, WE Fahl - Proceedings of the National …, 1997 - National Acad Sciences
… The transcriptional activation of the chemoprotective response genes by these … called the
antioxidant responsive element (ARE) (14), or, alternatively, the electrophile response element (…

[HTML][HTML] Antioxidant response elements: Discovery, classes, regulation and potential applications

A Raghunath, K Sundarraj, R Nagarajan, F Arfuso… - Redox biology, 2018 - Elsevier
… 3-MC, and Dioxin) but also electrophilic compounds (tert-butylhydroquinone, … element
responded surprisingly to an electrophilic signal, it was termed an electrophile-responsive element

[HTML][HTML] Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics

AL Levonen, BG Hill, E Kansanen, J Zhang… - Free Radical Biology …, 2014 - Elsevier
… During electrophile stress, Keap1 is no longer able to deliver Nrf2 to proteasomal … translocates
to the nucleus, binds to antioxidant response elements (AREs), and regulates target genes…

Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

JD Hayes, M McMahon - Cancer letters, 2001 - Elsevier
… The enhancer flanking mGsta1 was originally called an electrophile responsive element (EpRE)
because it can be stimulated by dimethyl fumarate and trans-4-phenyl-3-buten-2-one, …

Active defense under oxidative stress. The antioxidant responsive element

VV Lyakhovich, VA Vavilin, NK Zenkov… - Biochemistry …, 2006 - Springer
… of them are electrophilic (and so they are also known as elec trophile responsive element)
and may … Since hydroxylated phenolic acids exhibit marked antioxidant effect in various model …

Induction of xenobiotic enzymes by the map kinase pathway and the antioxidant or electrophile response element (ARE/EpRE),†,

ANT Kong, E Owuor, R Yu, V Hebbar… - Drug metabolism …, 2001 - Taylor & Francis
… BHA and tBHQ are both well-known phenolic antioxidants … ARE/EpRE (antioxidant/electrophile
response element), with … pathway via an electrophilic-mediated stress response, leading …

Activation of antioxidant/electrophile-responsive elements in IMR-32 human neuroblastoma cells

JD Moehlenkamp, JA Johnson - Archives of biochemistry and biophysics, 1999 - Elsevier
… and electrophiles called the antioxidant-responsive element (… named the electrophile-responsive
element (EpRE) by Friling … the core antioxidant/electrophileresponsive element (ARE/…