Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element

T Nishinaka, Y Ichijo, M Ito, M Kimura, M Katsuyama… - Toxicology letters, 2007 - Elsevier
… The major lines of evidence provided in this study are as follows: (1) The curcumin-induced
activation was suppressed by the introduction of dominant negative Nrf2. (2) Introduction of …

Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element: degradation of Nrf2 by the 26 S …

T Nguyen, PJ Sherratt, HC Huang, CS Yang… - Journal of Biological …, 2003 - ASBMB
activation of many genes encoding phase II drug-metabolizing enzymes via the
antioxidant response element… transfected with theGSTA2 antioxidant response element-chloramphenicol …

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in …

AD Kraft, DA Johnson, JA Johnson - Journal of Neuroscience, 2004 - Soc Neuroscience
… to the antioxidant response element (ARE) in neural cells results in the induction of a battery
of genes that can coordinate a protective response … were used as activators of this pathway. …

The antioxidant/electrophile response element motif

DE Nerland - Drug metabolism reviews, 2007 - Taylor & Francis
… to a DNA recognition sequence known as antioxidant response element (ARE) or electrophile
… Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-…

Transcriptional activation of the human Gαi2 gene promoter through nuclear factor-κB and antioxidant response elements

IJ Arinze, Y Kawai - Journal of Biological Chemistry, 2005 - ASBMB
… Taken together, the present studies reveal that transcription factors that bind NF-κB and/or
antioxidant response elements play an activating role in the transcription of the human Gα i2 …

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

MK Kwak, K Itoh, M Yamamoto… - Molecular and cellular …, 2002 - Am Soc Microbiol
… of protective enzymes is mediated in part by the antioxidant response element (ARE), a cis-…
cells enhanced the basal and inducible transcriptional activation of an ARE reporter gene (…

Activation of the antioxidant response element by specific oxidized metabolites of linoleic acid

R Wang, JT Kern, TL Goodfriend, DL Ball… - … and essential fatty acids, 2009 - Elsevier
Linoleic acid is required for normal mammalian health and development, but is also prone to
oxidation, yielding metabolites with biological effects. We screened linoleic acid, other fatty …

… activation by polycyclic aromatic hydrocarbons: evidence for the involvement of stress-activated protein kinases, activator protein-1, and antioxidant response …

D Ng, N Kokot, T Hiura, M Faris, A Saxon… - The Journal of …, 1998 - journals.aai.org
Activation of mitogen-activated protein kinases was dependent on generation of oxidative …
Another genetic response pathway linked to PAH is the antioxidant response element (ARE), …

In Vitro and in Vivo Regulation of Antioxidant Response Element-Dependent Gene Expression by Estrogens

PJ Ansell, C Espinosa-Nicholas, EM Curran… - …, 2004 - academic.oup.com
… DNA sequence, the antioxidant response element (ARE). It … is through activation of the bzip
transcription factor Nrf2 (18). … can bind directly to estrogen response elements (EREs) in the …

Regulation of Antioxidant Response Element–Dependent Induction of Detoxifying Enzyme Synthesis

AK Jaiswal - Methods in enzymology, 2004 - Elsevier
… induction of these genes in response to xenobiotics and antioxidants.15, 16 The NQO1 and
… imperfect activator protein 1 (AP1) (TPA response element) element. These elements are …