Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element
T Nishinaka, Y Ichijo, M Ito, M Kimura, M Katsuyama… - Toxicology letters, 2007 - Elsevier
… The major lines of evidence provided in this study are as follows: (1) The curcumin-induced
activation was suppressed by the introduction of dominant negative Nrf2. (2) Introduction of …
activation was suppressed by the introduction of dominant negative Nrf2. (2) Introduction of …
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element: degradation of Nrf2 by the 26 S …
T Nguyen, PJ Sherratt, HC Huang, CS Yang… - Journal of Biological …, 2003 - ASBMB
… activation of many genes encoding phase II drug-metabolizing enzymes via the
antioxidant response element… transfected with theGSTA2 antioxidant response element-chloramphenicol …
antioxidant response element… transfected with theGSTA2 antioxidant response element-chloramphenicol …
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in …
AD Kraft, DA Johnson, JA Johnson - Journal of Neuroscience, 2004 - Soc Neuroscience
… to the antioxidant response element (ARE) in neural cells results in the induction of a battery
of genes that can coordinate a protective response … were used as activators of this pathway. …
of genes that can coordinate a protective response … were used as activators of this pathway. …
The antioxidant/electrophile response element motif
DE Nerland - Drug metabolism reviews, 2007 - Taylor & Francis
… to a DNA recognition sequence known as antioxidant response element (ARE) or electrophile
… Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-…
… Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-…
Transcriptional activation of the human Gαi2 gene promoter through nuclear factor-κB and antioxidant response elements
IJ Arinze, Y Kawai - Journal of Biological Chemistry, 2005 - ASBMB
… Taken together, the present studies reveal that transcription factors that bind NF-κB and/or
antioxidant response elements play an activating role in the transcription of the human Gα i2 …
antioxidant response elements play an activating role in the transcription of the human Gα i2 …
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter
MK Kwak, K Itoh, M Yamamoto… - Molecular and cellular …, 2002 - Am Soc Microbiol
… of protective enzymes is mediated in part by the antioxidant response element (ARE), a cis-…
cells enhanced the basal and inducible transcriptional activation of an ARE reporter gene (…
cells enhanced the basal and inducible transcriptional activation of an ARE reporter gene (…
Activation of the antioxidant response element by specific oxidized metabolites of linoleic acid
R Wang, JT Kern, TL Goodfriend, DL Ball… - … and essential fatty acids, 2009 - Elsevier
Linoleic acid is required for normal mammalian health and development, but is also prone to
oxidation, yielding metabolites with biological effects. We screened linoleic acid, other fatty …
oxidation, yielding metabolites with biological effects. We screened linoleic acid, other fatty …
… activation by polycyclic aromatic hydrocarbons: evidence for the involvement of stress-activated protein kinases, activator protein-1, and antioxidant response …
D Ng, N Kokot, T Hiura, M Faris, A Saxon… - The Journal of …, 1998 - journals.aai.org
… Activation of mitogen-activated protein kinases was dependent on generation of oxidative …
Another genetic response pathway linked to PAH is the antioxidant response element (ARE), …
Another genetic response pathway linked to PAH is the antioxidant response element (ARE), …
In Vitro and in Vivo Regulation of Antioxidant Response Element-Dependent Gene Expression by Estrogens
PJ Ansell, C Espinosa-Nicholas, EM Curran… - …, 2004 - academic.oup.com
… DNA sequence, the antioxidant response element (ARE). It … is through activation of the bzip
transcription factor Nrf2 (18). … can bind directly to estrogen response elements (EREs) in the …
transcription factor Nrf2 (18). … can bind directly to estrogen response elements (EREs) in the …
Regulation of Antioxidant Response Element–Dependent Induction of Detoxifying Enzyme Synthesis
AK Jaiswal - Methods in enzymology, 2004 - Elsevier
… induction of these genes in response to xenobiotics and antioxidants.15, 16 The NQO1 and
… imperfect activator protein 1 (AP1) (TPA response element) element. These elements are …
… imperfect activator protein 1 (AP1) (TPA response element) element. These elements are …