Application of dendrimerdrug complexation in the enhancement of drug solubility and bioavailability

NK Jain, U Gupta - Expert opinion on drug metabolism & toxicology, 2008 - Taylor & Francis
Drugs form non-covalent inclusion complex with dendrimers and interact electrostatically and
… The non-covalent complexation can be achieved by incubation of drug and dendrimers in …

Dendrimers as versatile platform in drug delivery applications

S Svenson - European Journal of Pharmaceutics and …, 2009 - Elsevier
… Interestingly, when equal amounts of free prulifloxacin and prulifloxacin complexed to G4
PAMAM dendrimer were tested, it was found that prulifloxacine–PAMAM complexes were more …

[PDF][PDF] Pharmaceutical applications of dendrimers: promising nanocarriers for drug delivery

Y Cheng, J Wang, T Rao, X He, T Xu - Front Biosci, 2008 - article.imrpress.com
… cancer drugs is discussed. Three possible interaction mechanisms between dendrimers and
drug … properties of both dendrimer/drug complex and dendrimer-drug conjugation after their …

Dendrimerdrug interactions

A D'Emanuele, D Attwood - Advanced drug delivery reviews, 2005 - Elsevier
… architecture and the electrostatic and covalent complexation of drugs to the dendrimer
surface. The application of dendrimerdrug complexation in the enhancement of drug solubility …

[PDF][PDF] Dendrimer applications–a review

HN Patel, PM Patel - Int J Pharm Bio Sci, 2013 - Citeseer
… Jain NK and Gupta U, Application of dendrimer-drug complexation in the enhancement of
drug solubility and bioavailability, Expert Opin Drug Metab Toxicol, 8, 1035-1045,(2008). 52. …

Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

K Madaan, S Kumar, N Poonia, V Lather… - Journal of Pharmacy …, 2014 - journals.lww.com
… delivery and targeting, gene delivery and other biomedical applications, interactions involved
in formation of drug-dendrimer complex along with characterization techniques employed …

Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

AR Menjoge, RM Kannan, DA Tomalia - Drug discovery today, 2010 - Elsevier
complex or encapsulate therapeutic drugs or imaging moieties. As a delivery vector, the
dendrimer … determining optimum drug delivery to disease sites by conserving active drug efficacy …

Dendrimers in oral drug delivery application: current explorations, toxicity issues and strategies for improvement

Y Liu, JK Tee, G NC Chiu - Current pharmaceutical design, 2015 - ingentaconnect.com
… conjugation or complex to deliver the drug. In this review, application of dendrimers in oral
drug … to design a more desirable dendrimer-based delivery system that fits the need in oral …

Dendrimers as drug carriers: applications in different routes of drug administration

Y Cheng, Z Xu, M Ma, T Xu - Journal of pharmaceutical sciences, 2008 - Elsevier
… addition, blood drug level studies revealed that the drugdendrimer complex and 2.48 times
higher for the diflunisal‐PAMAM dendrimer complex, respectively, than that in the pure drug

Applications of dendrimers in drug delivery agents, diagnosis, therapy, and detection

B Noriega-Luna, LA Godínez… - Journal of …, 2014 - Wiley Online Library
dendrimers as drug carriers of ketoprofen by in vitro and in vivo studies. The in vitro release
of ketoprofen from the drug-dendrimer complex … the ketoprofen-PAMAM dendrimer complex. …