Application of dendrimerdrug complexation in the enhancement of drug solubility and bioavailability

NK Jain, U Gupta - Expert opinion on drug metabolism & toxicology, 2008 - Taylor & Francis
… of dendrimers further increase the solubility of insoluble drugs. Aqueous solubility of … -OH,
and G4.5 ester terminated PAMAM dendrimers. It was observed that at pH 7 aqueous …

[PDF][PDF] Dendrimer applications–a review

HN Patel, PM Patel - Int J Pharm Bio Sci, 2013 - Citeseer
… Cisplatin was complexed to the surface groups of a carboxylate-terminated PAMAM
dendrimer which led to a tenfold increase in the solubility of cisplatin compared to the free …

Dendrimers as versatile platform in drug delivery applications

S Svenson - European Journal of Pharmaceutics and …, 2009 - Elsevier
… The observed order of increased solubility in PAMAM dendrimers at a constant dendrimer
concentration and generation was naproxen > ketoprofen > ibuprofen > diflunisal [40]. …

Dendrimers for enhanced drug solubilization

S Svenson, AS Chauhan - Nanomedicine, 2008 - Taylor & Francis
dendrimers to enhance the solubility of poorly water-solubledendrimerdrug interaction
has to be selected based on the desired application: if the objective is enhanced water solubility

Dendrimer for solubility enhancement

B Gorain, M Pandey, H Choudhury, GK Jain… - Dendrimer-based …, 2021 - Elsevier
… on the solubility enhancement of drug candidates with special emphasis on the dendrimer-based
Application of dendrimers in the improvement of solubility of antitumor agents, anti-HIV, …

[HTML][HTML] Impact of dendrimers on solubility of hydrophobic drug molecules

S Choudhary, L Gupta, S Rani, K Dave… - Frontiers in …, 2017 - frontiersin.org
… , clinical and commercial applications of this approach in the field of drug development and
dendrimer has been used as a drug solubility enhancer; however, several other dendrimer

[HTML][HTML] Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
drugs cannot be exploited because of their poor solubility, toxicity or stability problems. The
use of dendrimers as … can solve these problems, thus improving their clinical applications [7]. …

Dendrimers as drug carriers: applications in different routes of drug administration

Y Cheng, Z Xu, M Ma, T Xu - Journal of pharmaceutical sciences, 2008 - Elsevier
… groups permit the application of dendrimers to enhance the solubility of many drugs. , 36 …
thus dendrimers can be modified or conjugated with a series of interesting guest molecules. …

[HTML][HTML] Dendrimers for drug delivery

AS Chauhan - Molecules, 2018 - mdpi.com
Application of dendrimers as a drug delivery system started … , whereas drugs are covalently
coupled on dendrimers in the … utility of PAMAM dendrimers for enhancing solubility, stability …

Nanotechnology in pharmaceutical and biomedical applications: Dendrimers

P SZYMAŃSKI, M Markowicz, E MIKICIUK-OLASIK - Nano, 2011 - World Scientific
Dendrimers application as drug carriers improves pharmacokinetic properties of drug particles,
decreases drugs… of ibuprofen, PAMAM dendrimers increase the drug solubility more than …