Synthesis of novel dendrimers having aspartate grafts and their ability to enhance the aqueous solubility of model drugs

L Ouyang, L Ma, B Jiang, Y Li, D He, L Guo - European journal of medicinal …, 2010 - Elsevier
dendrimers with different cores were synthesized in a convergent approach and well
characterized by NMR and MS techniques. The aqueous solubility … this kind of dendrimers at room …

Dendrimers: novel polymeric nanoarchitectures for solubility enhancement

U Gupta, HB Agashe, A Asthana, NK Jain - Biomacromolecules, 2006 - ACS Publications
… by which a dendrimer exerts its solubilizing property. … solubility enhancement using dendrimers.
Also, micellar behavior and future possibilities in relation to solubilization via dendrimers

Design and synthesis of novel amphiphilic Janus dendrimers for bone-targeted drug delivery

J Pan, M Wen, D Yin, B Jiang, D He, L Guo - Tetrahedron, 2012 - Elsevier
… In this paper, we synthesized a range of amphiphilic Janus dendrimers, … solubility data
indicated that amphiphilic Janus dendrimer is a favorable approach to deliver poor water-soluble

Synthesis and evaluation of novel dendrimers with a hydrophilic interior as nanocarriers for drug delivery

RS Dhanikula, P Hildgen - Bioconjugate chemistry, 2006 - ACS Publications
… cavity of the dendrimer will not only increase the size of the cavity but also will provide the
dendrimers ability to encapsulate both water soluble and poorly water soluble compounds, in …

Synthesis of amphiphilic Janus dendrimer and its application in improvement of hydrophobic drugs solubility in aqueous media

F Najafi, M Salami-Kalajahi… - European Polymer …, 2020 - Elsevier
… method for synthesis of Janus dendrimers without production of conventional dendrimers.
The … In this work, a new, simple and novel approach has been introduced to synthesize Janus …

[PDF][PDF] PAMAM dendrimers: novel polymeric nanoarchitectures for solubility enhancement of candesartan cilexetil

SP Gautam, A Verma - Pharmaceutical Sciences, 2012 - researchgate.net
… candidate for the solubility study. This study is an effort to increase the solubility of
Candesartan Cilexetil using PAMAM dendrimers. Hence, the present work might be helpful for the …

The effect of PAMAM dendrimer generation size and surface functional group on the aqueous solubility of nifedipine

B Devarakonda, RA Hill, MM de Villiers - International journal of …, 2004 - Elsevier
… lower generation ethylenediamine core PAMAM dendrimers on the aqueous solubility of the
hydrophobic drug … PAMAM dendrimers on the aqueous solubility of nifedipine was studied. …

Polyamidoamine Starburst® dendrimers as solubility enhancers

OM Milhem, C Myles, NB McKeown, D Attwood… - International journal of …, 2000 - Elsevier
… In conclusion, PAMAM dendrimers enhance the solubility of ibuprofen to a much greater extent
… Evidence that the solubility increase involves electrostatic interaction between dendrimer

[PDF][PDF] A review about dendrimers: synthesis, types, characterization and applications

T Baig, J Nayak, V Dwivedi, A Singh… - International Journal of …, 2015 - academia.edu
… Fully aromatic, watersoluble dendrimers forming a collection of aromatic polymeric chain …
novel ―fourth building class of polymers‖ and confirms the high buoyancy for the future of …

Polyamidoamine dendrimers as potential drug carriers for enhanced aqueous solubility and oral bioavailability of silybin

X Huang, Z Wu, W Gao, Q Chen… - Drug development and …, 2011 - Taylor & Francis
… effect of polyamidoamine (PAMAM) dendrimers on the solubility of silybin was … –dendrimer
complex were also investigated. Methods: The solubilization of silybin by PAMAM dendrimers