… , and Aspergillus species (1, 2, 15). In an experimental model of disseminated aspergillosis,
… of voriconazole against a range of clinical isolates of Aspergillus spp. and its efficacy in a rat …

… The theory that blood may contain substances that inhibit growth of conidia and hyphae
is unlikely, because blood agar is an excellent culture medium for Aspergillus species [1]. …

… , inoculum size and aspergillus species used are constant factors in our model. Thus,
efficacy of a test medication is the only factor that may improve survival of experimental animals. …

… Clinical and experimental data indicated differences in efficacy against … Aspergillus
species used in the present study had the same MIC (0.5 mg/liter), the new in vitro PK/PD model …

… an experimental model of invasive pulmonary aspergillosis. Copies/ml and CFU/ml of BAL
fluid are shown for real-time PCR assays (pan-Aspergillus [… in experimental models for only A. …

… It has been reported that some Aspergillus species other than A. fumigatus might be less
susceptible to currently used antifungal agents. Indeed, a reduced susceptibility to amphotericin …

… Nevertheless, the clinical impact of their reduced in vitro susceptibility remains to be
determined, as clinical experience is limited and experimental models are lacking. …

… A lack of experimental systems has limited our understanding of the pathobiology and
management of noninvasive airway disease due to Aspergillus species. Animal models are useful …

… One limitation of the present model is that we were unable to compare SCH51048 with …
against various fungi, including Aspergillus species (5). With the present model, despite good in …

… Only few Aspergillus species are known to be pathogenic for man, among which A. fumigatus
… experimental models of IA or for estimating the infectivity of inhaled spores of Aspergillus. …