Human DNA methylomes at base resolution show widespread epigenomic differences
… between the DNA methylomes of two human cell types, revealing the highly dynamic nature
of this epigenetic modification. The genomic context of the DNA methylation is resolved, …
of this epigenetic modification. The genomic context of the DNA methylation is resolved, …
Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes
… enabled investigators to profile genome methylation patterns at single-base resolution.
Remarkably, more than 20 eukaryotic methylomes have been generated thus far, with a majority …
Remarkably, more than 20 eukaryotic methylomes have been generated thus far, with a majority …
'Leveling'the playing field for analyses of single-base resolution DNA methylomes
… of DNA methylation, collectively referred to as whole-genome bisulfite sequencing (WGBS).
Single-base resolution DNA methylomes are … for the detection of cytosine DNA methylation [ …
Single-base resolution DNA methylomes are … for the detection of cytosine DNA methylation [ …
[HTML][HTML] The DNA methylome
M Pelizzola, JR Ecker - FEBS letters, 2011 - Elsevier
… However, base-resolution iPSCs DNA methylomes are not yet available. Several studies
have shown that methylation profiles of iPSCs are aberrant with respect to those of embryonic …
have shown that methylation profiles of iPSCs are aberrant with respect to those of embryonic …
Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis
… ) are commonly used for base resolution DNA methylome research. Although multiple tools
… compares the pros and cons of each in methylome profiling. We then discuss approaches to …
… compares the pros and cons of each in methylome profiling. We then discuss approaches to …
Generating multiple base-resolution DNA methylomes using reduced representation bisulfite sequencing
A Chatterjee, EJ Rodger, PA Stockwell… - Oral Biology: Molecular …, 2017 - Springer
… to generate base-resolution methylomes. Furthermore, we provide a brief guideline for
base-… These strategies will be useful to perform large-scale, genome-wide DNA methylation …
base-… These strategies will be useful to perform large-scale, genome-wide DNA methylation …
[HTML][HTML] Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes
CWQ Koh, YT Goh, WSS Goh - Nature communications, 2019 - nature.com
… We envision that an atlas of single-base-resolution methylomes in different cell types will
help elucidate demethylase specificity mechanisms and identify new forms of epitranscriptomics…
help elucidate demethylase specificity mechanisms and identify new forms of epitranscriptomics…
[HTML][HTML] Single-base resolution maps of cultivated and wild rice methylomes and regulatory roles of DNA methylation in plant gene expression
… To examine the rice genomic methylation landscape and assess its functional significance,
we generated single-base resolution DNA methylome maps for Asian cultivated rice Oryza …
we generated single-base resolution DNA methylome maps for Asian cultivated rice Oryza …
MethBank: a database integrating next-generation sequencing single-base-resolution DNA methylation programming data
… -base nucleotide measurement of DNA methylation and accordingly the generation of
genome-… high-resolution DNA methylome. The comprehensive integration of DNA methylomes in …
genome-… high-resolution DNA methylome. The comprehensive integration of DNA methylomes in …
[HTML][HTML] DNA methylome profiling of circulating tumor cells in lung cancer at single base-pair resolution
L Zhao, X Wu, J Zheng, D Dong - Oncogene, 2021 - nature.com
… samples, and will facilitate the investigation of CTC DNA methylome. Second, this method is
… the CTC DNA methylome at single base resolution, which can discover a unique “CTC DNA …
… the CTC DNA methylome at single base resolution, which can discover a unique “CTC DNA …
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