Benzo [a] pyrene decreases global and gene specific DNA methylation during zebrafish development

X Fang, C Thornton, BE Scheffler, KL Willett - Environmental toxicology and …, 2013 - Elsevier
… direct waterborne benzo[a]pyrene (BaP) exposure at 24 μg/L from 2.5 to 96 hpf to zebrafish
… epigenetic modifier for global and gene specific DNA methylation status in zebrafish larvae. …

[HTML][HTML] Mixture effects of oxygenated PAHs and benzo [a] pyrene on cardiovascular development and function in zebrafish embryos

V Cunha, C Vogs, F Le Bihanic, K Dreij - Environment International, 2020 - Elsevier
… In this study, we used zebrafish embryos (ZFEs) as a model to examine developmental and
… /oxy-PAH mixtures on the developing zebrafish embryo with focus on the cardiotoxicity of …

Multigenerational effects of benzo [a] pyrene exposure on survival and developmental deformities in zebrafish larvae

J Corrales, C Thornton, M White, KL Willett - Aquatic toxicology, 2014 - Elsevier
developmental effects following exposure to PAHs are in need of exploration. Benzo[a]pyrene
(… Here adult zebrafish (F0) were fed 0, 10, 114, or 1012 μg BaP/g diet at a feed rate of 1% …

Benzo [a] pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos

L Huang, C Wang, Y Zhang, J Li, Y Zhong, Y Zhou… - Chemosphere, 2012 - Elsevier
development and disease is unclear. In the present study, the cardiac morphology and
functioning of zebrafish embryos exposed to benzo[a]pyrene [… developmental defects in zebrafish

Nephrotoxicity assessments of benzo (a) pyrene during zebrafish embryogenesis

KC Lo, CY Sun, YJ Ding, JN Tsai, KP Chang… - Research on Chemical …, 2014 - Springer
… Because the teratogenic effect of benzo(a)pyrene on embryonic kidney development is
unclear, we here used Tg(wt1b:GFP) as a model system to perform a dose-dependent …

Developmental benzo [a] pyrene (B [a] P) exposure impacts larval behavior and impairs adult learning in zebrafish

AL Knecht, L Truong, MT Simonich… - Neurotoxicology and …, 2017 - Elsevier
… Using the zebrafish model, we evaluated the developmental toxicity of … We used the
zebrafish model to evaluate the developmental and long term behavior effects of benzo[a]pyrene

Altered gene expression: A mechanism for reproductive toxicity in zebrafish exposed to benzo [a] pyrene

JL Hoffmann, JT Oris - Aquatic Toxicology, 2006 - Elsevier
benzo[a]pyrene (B[a]P) (0, 1.5 and 3.0 μg/L) for 56 days on egg production and OSI in female
zebrafish … composite of RT products from oocytes at each of the four stages of development. …

Transcriptomic changes in zebrafish embryos and larvae following benzo [a] pyrene exposure

X Fang, J Corrales, C Thornton, T Clerk… - Toxicological …, 2015 - academic.oup.com
… DNA methylation patterns in developing zebrafish, which may … gene expression and splicing
in developing zebrafish. Adult … reported ethanol effects on zebrafish development, and we …

Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo [a] pyrene in zebrafish

AL Knecht, L Truong, SW Marvel, DM Reif… - Toxicology and applied …, 2017 - Elsevier
… the effects of developmental B[a]P exposure on 3 generations of zebrafish. Zebrafish embryos
… B[a]P exposure during development resulted in decreased global DNA methylation levels …

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
… In addition to the BaP effects, this study provides important information related to
constitutive gene-specific complexity in promoter methylation during zebrafish development. …