Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - Biomedicines, 2022 - mdpi.com
drugs (APIs) exhibit poor solubility, lower bioavailability, and less dissolution. Various
technologies are discussed in this article to improve the solubility of poorly water-soluble drugs, for …

Pharmaceutical dispersion techniques for dissolution and bioavailability enhancement of poorly water-soluble drugs

X Zhang, H Xing, Y Zhao, Z Ma - Pharmaceutics, 2018 - mdpi.com
… -pass effect and increase the lipophilic drug’s absorption [18]. … of bioavailability enhancer
for poorly water-soluble drugstechniques for dissolution and bioavailability improvement has …

Various techniques of bioavailability enhancement: a review

AD Khan, L Singh - Journal of Drug Delivery and Therapeutics, 2016 - jddtonline.info
… Any drug to be absorbed must be present in the form of an aqueous solution at the site of …
various techniques used for the improvement of the Bioavailability of drugs. The various …

[PDF][PDF] Bioavailability enhancement of poorly water soluble drugs

AK Gupta, SK Sehrawat - IJRLS, 2011 - Citeseer
… For many new chemical entities with very low solubility, oral bioavailability enhancement
by micronization is not sufficient. Micronized product has the tendency to agglomerate, which …

[PDF][PDF] Pharmaceutical technologies for enhancing oral bioavailability of poorly soluble drugs

YSR Krishnaiah - J Bioequiv Availab, 2010 - researchgate.net
… A brief review of the technologies along with a few reports is … in enhancing the oral
bioavailability of poorly soluble drugs. … for enhancing the bioavailability of poorly soluble drugs. …

Enhancement of solubilization and bioavailability of poorly soluble drugs by physical and chemical modifications: A recent review

A Chaudhary, U Nagaich, N Gulati, VK Sharma… - Journal of Advanced …, 2012 - japer.in
… to improve the solubility and bioavailability of poorly soluble drugs by using various approaches
like physical, chemical and others modifications or techniques. The solubility of a solute …

[PDF][PDF] Technologies to improve the solubility, dissolution and bioavailability of poorly soluble drugs

N Kanikkannan - J. Anal. Pharm. Res, 2018 - researchgate.net
… About 40% of drugs developed by Pharma industry and about 90% of the drugs in development
pipeline are poorly soluble drugs [1]. Drug solubility and bioavailability enhancement

[PDF][PDF] Techniques for bioavailability enhancement of BCS class II drugs: a review

N Singh, D Allawadi, S Singh… - International Journal of …, 2013 - researchgate.net
… permeability of poorly permeable drugs In this article, the various techniques that that can
be used for solubility enhancement of BCS Class II drugs are discussed in this article with …

[PDF][PDF] Review on solubility enhancement techniques for hydrophobic drugs

A Kumar, SK Sahoo, K Padhee, PS Kochar… - Pharmacie …, 2011 - researchgate.net
soluble drugs are allied with slow drug absorption leading to inadequate and variable
bioavailability … novel techniques for enhancing drug solubility to reduce the percentage of poorly …

A recent review on bioavailability and solubility enhancement of poorly soluble drugs by physical and chemical modifications

L Devhare, PK Kore - Research chronicle in health sciences, 2016 - papers.ssrn.com
improvement of the solubility and bioavailability of poorly water soluble drugs by applying
various new methods… very low solubility, oral bioavailability enhancement by micronization is …