… wide patterns of DNA methylation, we focused mainly on the human genome. The following
top ics in DNA methylation will be treated in detail: (i) the de novo methylation of integrated …

… Although, in general, the biological significance of methylated bases in DNA is still an …
suggest that DNA methylation is, in one way or another, involved in major biological processes. …

… in eukaryotic DNA methylation; so that some 30 to 35 years after the great harvest in … DNA
methylation, very little is known about enzyme mechanisms, specific sites of methylation and …

… The change in DNA methylation could last for a long period of … in DNA methylation, however,
is not well understood yet. In order to clarify whether or not the change of DNA methylation …

… The key role of DNA methylation is to control gene expression, and methylated sequences
… of gene expression by DNA methylation, with an emphasis on cell biological aspects and a …

… Thus we include the doubts and the certainties as well as the challenges that still have to
be met if we are to understand the whole biological significance of DNA methylation. …

… on DNA methylation and DNA methyltransferases with emphasis on how biological and …
in modulating DNA methylation. Other physiological and biochemical factors that can modify …

… DNA methylation and their biological significance will be discussed in later sections. In satellite
DNA, being heavily methylated, the extent of methylation … pattern of methylation may vary …

… DNA methylation (methylome) have broadened our understanding of the biological significance
of CGIs and methylation. … been applied toward mapping DNA methylation genome wide (…

… methylation patterns suggests that DNA methylation patterns are inherited during replication.
This is because the DNA … CpG moieties (maintenance methylation) but relatively inefficient …