[HTML][HTML] The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder

Y Xiao, C Camarillo, Y Ping, TB Arana, H Zhao… - PloS one, 2014 - journals.plos.org
… Finally, we combined DNA methylome and transcriptome to explore their possible links in …
Importantly, numerous abnormal biological processes inferred from DNA methylome were …

[HTML][HTML] The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder

AL Comes, D Czamara, K Adorjan… - … of bipolar disorders, 2020 - Springer
… role of DNA methylation in response to recent stressful life events in a cohort of bipolar
patients from the longitudinal PsyCourse study (n = 96). Peripheral blood DNA methylomes were …

… analyses of the candidate genes identified by a methylome‐wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder

H Sugawara, Y Murata, T Ikegame… - Psychiatry and …, 2018 - Wiley Online Library
Aim Schizophrenia (SZ) and bipolar disorder (BD) have been known to share genetic and
environmental risk factors, and complex gene–environmental interactions may contribute to …

Genome‐Wide Methylome Analyses Reveal Novel Epigenetic Regulation Patterns in Schizophrenia and Bipolar Disorder

Y Li, C Camarillo, J Xu, TB Arana, Y Xiao… - BioMed research …, 2015 - Wiley Online Library
… In summary, we have used a high-throughput MeDIP-Seq strategy to characterize the DNA
methylome map of schizophrenia and bipolar disease. We observed distinct patterns of DNA

[HTML][HTML] DNA methylation in a Scottish family multiply affected by bipolar disorder and major depressive disorder

RM Walker, AN Christoforou, DL McCartney… - Clinical …, 2016 - Springer
Bipolar disorder (BD) is severe psychiatric condition characterised by recurrent episodes
of depression and mania. BD is highly heritable (h 2 = 0.85 [1]), and in recent years, progress …

[HTML][HTML] Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder

M Bundo, J Ueda, Y Nakachi, K Kasai, T Kato… - Molecular …, 2021 - nature.com
Bipolar disorder (BD) is a severe mental disorder characterized by repeated mood swings. …
We performed promoter-wide DNA methylation analysis of neuronal and nonneuronal nuclei …

The role of DNA methylation in the pathophysiology and treatment of bipolar disorder

GR Fries, Q Li, B McAlpin, T Rein, C Walss-Bass… - Neuroscience & …, 2016 - Elsevier
Bipolar disorder (BD) is a multifactorial illness thought to result from an interaction between
genetic susceptibility and environmental stimuli. Epigenetic mechanisms, including DNA

[HTML][HTML] … of treatment response variability in serious mental illnesses: a systematic review focused on bipolar disorder, schizophrenia, and major depressive disorder

C Goud Alladi, B Etain, F Bellivier… - International journal of …, 2018 - mdpi.com
… So far, genetic studies of treatment response in schizophrenia, bipolar disorder, and major
depression have returned results with limited clinical utility. A gene × environment interplay …

Differentially methylated regions in bipolar disorder and suicide

ME Gaine, F Seifuddin, S Sabunciyan… - American Journal of …, 2019 - Wiley Online Library
DNA methylation of CpG sites has been associated with many psychiatric disorders including
bipolar disorder … Using the SureSelect XT system, Methyl-Seq, we investigated the DNA

[HTML][HTML] DNA Methylation and Bipolar Disorder

Z Yang, S Zhang, L Ouyang, A Liao, Y He… - Journal of Psychiatry …, 2023 - jpbs.hapres.com
… using the keywords “bipolar disorder”, “bipolar affect disorder”, and “DNA methylation” limiting
the date … For the DNA methylome in human microglia, a study has identified various DMRs …