Multiple levels of epigenetic control for bone biology and pathology

M Montecino, G Stein, J Stein, K Zaidi, R Aguilar - Bone, 2015 - Elsevier
… the contribution of epigenetic control to the dynamic regulation of gene … the biology of
skeletal epigenetic control to paradigm shifting options with the diagnosis and treatment of bone

Epigenetic regulation of bone mass

EM Curtis, NR Fuggle, C Cooper, NC Harvey - Best Practice & Research …, 2022 - Elsevier
… of epigenetic mechanisms in disease etiology and pathology is a very complex process.
Histone modifications, non-coding RNAs and DNA methylation changes identified in human …

Epigenetic regulation of bone cells

KH Park-Min - Connective tissue research, 2017 - Taylor & Francis
… Increasing evidence suggests that epigenetic regulation plays an important role under
physiological and pathological conditions. It has become clear that epigenetic regulation is a key …

Epigenetics of skeletal diseases

A Del Real, L Riancho-Zarrabeitia… - Current Osteoporosis …, 2018 - Springer
… provide an overview of the role of epigenetic mechanisms in bone biology and pathology. …
of epigenetic mechanisms in bone biology, and specifically in the differentiation of bone cells. …

[HTML][HTML] Epigenetic regulation of skeletal tissue integrity and osteoporosis development

YS Chen, WS Lian, CW Kuo, HJ Ke, SY Wang… - International Journal of …, 2020 - mdpi.com
… that epigenetic modification controls bone cell survival, function, metabolism, and transformation
during skeletal tissue … , pathological, and clinical significance of epigenetic pathway in …

Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders

JAR Gordon, MA Montecino, RI Aqeilan… - Current osteoporosis …, 2014 - Springer
bone biology and pathologic disorders. Such knowledge has the potential to provide a basis
for therapy to reverse skeletal … of epigenetic controls in normal bone biology and in skeletal

Epigenetic pathways regulating bone homeostasis

JB Lian - Bone, 2015 - Elsevier
… of epigenetic control in bone biology as well as in … epigenetic regulation in skeletal cells.
Our objective is to encourage investigation that will assimilate basic bone biology and pathology

[HTML][HTML] Epigenetic control of skeletal development by the histone methyltransferase Ezh2

A Dudakovic, ET Camilleri, F Xu, SM Riester… - Journal of Biological …, 2015 - ASBMB
… profiles of a large cohort of epigenetic regulators (>300) during … in multiple defects in skeletal
patterning and bone formation, … that the epigenetic activity of EZH2 is required for skeletal

[HTML][HTML] Osteoblast versus adipocyte: bone marrow microenvironment-guided epigenetic control

J Li, B Zuo, L Zhang, L Dai, X Zhang - Case Reports in Orthopedic …, 2019 - karger.com
… Since the epigenetic mechanism also plays an important role … differentiation regulation [9],
this review will discuss how the bone … and pathological conditions, by epigenetic mechanisms. …

Epigenetic regulation of bone remodeling and bone metastasis

G Sharma, A Sultana, KM Abdullah, R Pothuraju… - … Developmental Biology, 2024 - Elsevier
… -drugs for advanced and bone metastasis cancer patients. This … about different epigenetic
modifications in bone remodeling … between bone formation and resorption creates pathological