The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder

Y Xiao, C Camarillo, Y Ping, TB Arana, H Zhao… - PloS one, 2014 - journals.plos.org
DNA methylome and transcriptome to explore their possible links in different brain regions
… Our results suggest that different brain regions exhibit completely different DNA methylation …

Common DNA methylation alterations in multiple brain regions in autism

C Ladd-Acosta, KD Hansen, E Briem, MD Fallin… - Molecular …, 2014 - nature.com
… Briefly, we performed individual methylome analyses for each of the three brain regions:
dorsolateral PFC (6 cases/5 controls), TC (6 cases/10 controls) and CBL (7 cases/6 controls) …

Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome

RS Illingworth, U Gruenewald-Schneider… - Nucleic acids …, 2015 - academic.oup.com
… We conclude that the cerebellar DNA methylome differs from other brain regions tested in
this study in two complementary ways: (i) methylation at specific CGIs, particularly those found …

Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain

H Liu, Q Zeng, J Zhou, A Bartlett, BA Wang, P Berube… - Nature, 2023 - nature.com
brain regions (Fig. 2). To further explore the spatial information in the DNA methylome, we …
-to-lateral axes in the brain using representative dissection regions (Extended Data Fig. 7a–c). …

The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging

NM Ghahramani, TC Ngun, PY Chen, Y Tian… - Biology of sex …, 2014 - Springer
… on the DNA methylome and transcriptome in two sexually dimorphic forebrain regions—the …
and persistence of sex differences in DNA methylation, we performed genome-wide surveys …

Opening up the DNA methylome of dementia

R Delgado-Morales, M Esteller - Molecular psychiatry, 2017 - nature.com
… Several laboratories have recently turned their attention to the role of the (hydroxy)methylome
of mtDNA and its function regulating gene expression. Little is known about brain mtDNA …

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

JV Sanchez-Mut, H Heyn, E Vidal, S Moran… - Translational …, 2016 - nature.com
… and unbiased DNA methylome by WGBS 19, 20 of an important and specific brain region—the …
We subtracted the DNA methylome of the white matter from the same area to identify the …

Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

M Devall, RG Smith, A Jeffries, E Hannon… - Clinical …, 2017 - Springer
… Using unsupervised hierarchical clustering analysis of the mitochondrial DNA methylome,
we were able to identify tissue-specific patterns of mitochondrial DNA methylation between …

Neuronal activity modifies the DNA methylation landscape in the adult brain

JU Guo, DK Ma, H Mo, MP Ball, MH Jang… - Nature …, 2011 - nature.com
… the neuronal DNA methylome is … regions, and were associated with brain-specific genes
related to neuronal plasticity. Our study implicates modification of the neuronal DNA methylome

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

MN Davies, M Volta, R Pidsley, K Lunnon, A Dixit… - Genome biology, 2012 - Springer
brain regions and blood obtained from multiple individuals. We present annotated maps of
the brain methylome, … communities, identifying key regions of the genome characterized by …