The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder
Y Xiao, C Camarillo, Y Ping, TB Arana, H Zhao… - PloS one, 2014 - journals.plos.org
… DNA methylome and transcriptome to explore their possible links in different brain regions
… Our results suggest that different brain regions exhibit completely different DNA methylation …
… Our results suggest that different brain regions exhibit completely different DNA methylation …
Common DNA methylation alterations in multiple brain regions in autism
… Briefly, we performed individual methylome analyses for each of the three brain regions:
dorsolateral PFC (6 cases/5 controls), TC (6 cases/10 controls) and CBL (7 cases/6 controls) …
dorsolateral PFC (6 cases/5 controls), TC (6 cases/10 controls) and CBL (7 cases/6 controls) …
Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome
RS Illingworth, U Gruenewald-Schneider… - Nucleic acids …, 2015 - academic.oup.com
… We conclude that the cerebellar DNA methylome differs from other brain regions tested in
this study in two complementary ways: (i) methylation at specific CGIs, particularly those found …
this study in two complementary ways: (i) methylation at specific CGIs, particularly those found …
Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain
… brain regions (Fig. 2). To further explore the spatial information in the DNA methylome, we …
-to-lateral axes in the brain using representative dissection regions (Extended Data Fig. 7a–c). …
-to-lateral axes in the brain using representative dissection regions (Extended Data Fig. 7a–c). …
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
… on the DNA methylome and transcriptome in two sexually dimorphic forebrain regions—the …
and persistence of sex differences in DNA methylation, we performed genome-wide surveys …
and persistence of sex differences in DNA methylation, we performed genome-wide surveys …
Opening up the DNA methylome of dementia
R Delgado-Morales, M Esteller - Molecular psychiatry, 2017 - nature.com
… Several laboratories have recently turned their attention to the role of the (hydroxy)methylome
of mtDNA and its function regulating gene expression. Little is known about brain mtDNA …
of mtDNA and its function regulating gene expression. Little is known about brain mtDNA …
Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns
… and unbiased DNA methylome by WGBS 19, 20 of an important and specific brain region—the …
We subtracted the DNA methylome of the white matter from the same area to identify the …
We subtracted the DNA methylome of the white matter from the same area to identify the …
Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue
… Using unsupervised hierarchical clustering analysis of the mitochondrial DNA methylome,
we were able to identify tissue-specific patterns of mitochondrial DNA methylation between …
we were able to identify tissue-specific patterns of mitochondrial DNA methylation between …
Neuronal activity modifies the DNA methylation landscape in the adult brain
… the neuronal DNA methylome is … regions, and were associated with brain-specific genes
related to neuronal plasticity. Our study implicates modification of the neuronal DNA methylome …
related to neuronal plasticity. Our study implicates modification of the neuronal DNA methylome …
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
… brain regions and blood obtained from multiple individuals. We present annotated maps of
the brain methylome, … communities, identifying key regions of the genome characterized by …
the brain methylome, … communities, identifying key regions of the genome characterized by …
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