… Furthermore, we detected transcriptome-wide gene expression changes between patients
… DNA methylome and transcriptome to explore their possible links in different brain regions …

… that simultaneously profiles both DNA methylome and transcriptome from the same cell. In
sensory neurons, we consistently identify transcriptome and methylome heterogeneity among …

… control group in all reference brain regions. In line with this, Aston … pole from patients with
MDD by transcriptome analysis [71]. Our … Consistent with our findings, previous transcriptome …

… -wide profiling of DNA methylome and transcriptome in purified blood monocytes from 79
MZ twin pairs discordant for lifetime history of MDD, followed by replication in brain tissue and …

… Using iterative clustering and integrating with companion whole-brain transcriptome and
chromatin accessibility datasets, we constructed a methylation-based cell taxonomy with 4,673 …

… The phenotypic variation may be partially due to sex differences in epigenomes and
transcriptomes in specific brain regions [eg the prefrontal cortex (PFC)]. Genome-wide DNA …

… We investigated the organizational effects of testosterone on the DNA methylome and
transcriptome in two sexually dimorphic forebrain regions—the bed nucleus of the stria terminalis/…

… brain aging result in cognitive impairment and susceptibility to neurodegenerative disease.
Changes in DNA … various CNS functions are observed with brain aging and can be prevented …

… We conclude that the cerebellar DNA methylome differs from other brain regions tested in
this study in two complementary ways: (i) methylation at specific CGIs, particularly those found …

… about the heterogeneity of the DNA methylome, its function in tumor biology, coupling with
the transcriptome and tumor microenvironment and its possible impact for tumor development. …