Targeting autophagy in breast cancer

S Cocco, A Leone, M Piezzo, R Caputo… - International journal of …, 2020 - mdpi.com
… of autophagy focusing on its interplay with targeted drugs used for breast cancer treatment.
… exhibit a higher level of autophagy than other breast cancer subtypes. Expression of the …

[HTML][HTML] Targeting autophagy in breast cancer

P Maycotte, A Thorburn - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
… recent findings relating autophagy and cancer with a particular focus on breast cancer therapy.
… be addressed before autophagy can be successfully targeted for breast cancer treatment. …

Therapeutic potential for targeting autophagy in ER+ breast cancer

RM Finnegan, AM Elshazly, PV Schoenlein… - Cancers, 2022 - mdpi.com
… clarify the value of targeting autophagy to reduce breast cancer metastatic disease, … autophagy
inhibitor. With regard to the role of autophagy in ER positive/Her 2 negative breast cancer

Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy

MY Zamanian, M Golmohammadi… - Fundamental & …, 2023 - Wiley Online Library
… of autophagy show a dual role in the development of cancer. Alternative therapies such as
targeting autophagy … can either stimulate or inhibit autophagy. Subsequently, upregulation of …

Autophagy: a promising target for triple negative breast cancers

YS Abd El-Aziz, J Gillson, PJ Jansson, S Sahni - Pharmacological research, 2022 - Elsevier
… The critical role of autophagy in TNBC progression is … autophagic pathway, how autophagy
affects TNBC progression and recent therapeutic approaches that can target autophagy as a …

Targeting autophagy in cancer

AV Onorati, M Dyczynski, R Ojha, RK Amaravadi - Cancer, 2018 - Wiley Online Library
cancers. In this review of the literature, the authors present fundamental advances in the
biology of autophagy, approaches to targeting autophagy, … mouse model of breast cancer.35, 36 …

[HTML][HTML] Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

M Dyczynski, Y Yu, M Otrocka, S Parpal, T Braga… - Cancer letters, 2018 - Elsevier
… of two breast cancer cell … autophagy significantly improves sensitivity to Sunitinib and Erlotinib
and that Vps34 is a promising therapeutic target for combination strategies in breast cancer

Hormone-dependent breast cancer: Targeting autophagy and PI3K overcomes Exemestane-acquired resistance

C Amaral, TV Augusto, E Tavares-da-Silva… - The Journal of steroid …, 2018 - Elsevier
… Our results confirmed that Exe induced autophagy in acquired resistant breast cancer cells,
… are typical morphological/biochemical features of the autophagic process. In this process, pro…

Targeting autophagy in cancer

JMM Levy, CG Towers, A Thorburn - Nature Reviews Cancer, 2017 - nature.com
autophagy-focused clinical studies. This convergence will allow us to better target autophagy
to improve clinical outcomes in cancerbreast cancer cells grow well when autophagy is …

Attacking breast cancer at the preinvasion stage by targeting autophagy

V Espina, J Wysolmerski, K Edmiston… - Women's …, 2013 - journals.sagepub.com
autophagy (‘self-eating’) is a major survival strategy used by preinvasive carcinoma and
breast cancer … for preinvasive neoplastic cells, and thereby stop breast cancer before it starts. …