Alterations in glycosylation as biomarkers for cancer detection

CA Reis, H Osorio, L Silva, C Gomes… - Journal of clinical …, 2010 - jcp.bmj.com
Cancer is associated with glycosylation alterations in glycoproteins and glycolipids. This …
of protein glycosylation with the focus on alterations associated with human cancer. The …

Glycosylation markers in cancer

A Silsirivanit - Advances in clinical chemistry, 2019 - Elsevier
… has been associated with alteration of glycosylation patterns that … Altered glycosylation pattern
is a hallmark of cancer. Many … In this chapter, the alteration of protein glycosylation and the …

Altered glycosylation in tumours focused to cancer diagnosis

R Peracaula, S Barrabés, A Sarrats, PM Rudd… - Disease …, 2008 - content.iospress.com
… polarization of epithelial cells in cancer results in the release of the glycoproteins and
mucins into the bloodstream. The detection of the altered glycosylation of these serum proteins …

Altered glycosylation in cancer: A promising target for biomarkers and therapeutics

D Thomas, AK Rathinavel, P Radhakrishnan - … (BBA)-Reviews on Cancer, 2021 - Elsevier
… a promising research area for cancer biomarker identification. This … how altered glycosylation
machinery is associated with cancer … of aberrant glycosylation in the development of cancer

Altered glycosylation in prostate cancer

RR Drake, EE Jones, TW Powers… - Advances in cancer …, 2015 - Elsevier
… Additionally, these detection methods for global alterations in glycosylation require staining
on many adjacent tissue sections, making large scale assessments on many samples difficult…

Clinical aspects of altered glycosylation of glycoproteins in cancer

TF Orntoft, EM Vestergaard - … : An International Journal, 1999 - Wiley Online Library
… Although the alterations differ from tissue to tissue, a universal hallmark of cancer cells is a
change in glycosylation phenotype. With one exception (O-GlcNAc) the altered glycosylation

Glycosylation in cancer: Selected roles in tumour progression, immune modulation and metastasis

JG Rodrigues, M Balmaña, JA Macedo, J Poças… - Cellular …, 2018 - Elsevier
… In this review, we address the role of altered protein N-glycosylation, O-glycosylation, …
glycoconjugates as well as the function of key glycan binding proteins in cancer metastasis. …

Aberrant glycosylation associated with enzymes as cancer biomarkers

DL Meany, DW Chan - Clinical proteomics, 2011 - Springer
cancer biomarker discovery using aberrant glycosylation in three areas. First, changes in
glycosylation … [44] initially demonstrated this possibility--that altered glycosylation patterns allow …

Glycosylation changes in prostate cancer progression

W Butler, J Huang - Frontiers in oncology, 2021 - frontiersin.org
… changes in branching, altered levels of Lewis and … altered N- and O-linked glycosylation in
PCa tissue and body fluids. We further discuss changes in O-GlcNAcylation as well as altered

Glycosylation changes in brain cancer

L Veillon, C Fakih, H Abou-El-Hassan… - ACS chemical …, 2018 - ACS Publications
… Protein glycosylation is a posttranslational modification that affects more than half of all …
discussion of aberrant glycosylation related to brain cancer. Altered sialylation and fucosylation …