… a conducive tumor environment. As EV-associated miRNAs are tissue-specific and present
in most biological fluids, they hold great potential for clinical application in cancer early …

… Among the multitude of exosome-based trials, the last example we want to report concerns
the use of exosomes in vaccines for cancer immunotherapy. An interventional phase 2 “Trial …

Both normal and diseased cells continuously shed extracellular vesicles (EVs) into extracellular
space, and the EVs carry molecular signatures and effectors of both health and disease. …

… promising in their potential for clinical application, and a number of clinical trials investigating
specific sEV protein biomarkers for diagnosis or prognosis of various cancers have been …

… the role of EVs in tumor development and metastasis and their possible applications in the
… Furthermore, the latest progress in the potential clinical applications of EVs were discussed. …

… Small extracellular vesicles (sEVs) were initially recognized as cellular debris and …
roles of cancer-derived sEVs in CRC carcinogenesis and their clinical applications in CRC …

… process in lung cancer. Furthermore, we present the most recent applications for EVs
and non-coding RNAs as cancer therapeutics and their relevance as clinical biomarkers. …

… use in cancer treatment from bench to bedside, to provide an updated overview of EVs’ clinical
uses… is a crucial challenge for achieving clinical applications of EVs in cancer. Despite the …

… already identified in tumor-EVs and discussed their known function in cancer and how
they … Finally, we highlight the potential clinical application of the EV glycosylation in anti-cancer …

… We believe that several clinical trials to employ EVs in the diagnosis of cancer will begin
over the next five years. The cost of medicine is the largest issue worldwide, and a recent report …