TRIBUTE-A phase III trial of erlotinib HCl (OSI-774) combined with carboplatin and paclitaxel (CP) chemotherapy in advanced non-small cell lung cancer (NSCLC)
RS Herbst, D Prager, R Hermann, V Miller… - Journal of Clinical …, 2004 - ascopubs.org
… as leading to death (53 erlotinib; 27 PBO). Only 5 of … Erlotinib combined with carboplatin
and paclitaxel chemotherapy did not confer a survival advantage over carboplatin and paclitaxel …
and paclitaxel chemotherapy did not confer a survival advantage over carboplatin and paclitaxel …
TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non–small-cell lung cancer
RS Herbst, D Prager, R Hermann… - Journal of clinical …, 2005 - ascopubs.org
… Erlotinib with concurrent carboplatin and paclitaxel did not confer a survival advantage over
carboplatin and paclitaxel … Never smokers treated with erlotinib and chemotherapy seemed …
carboplatin and paclitaxel … Never smokers treated with erlotinib and chemotherapy seemed …
Phase I, pharmacokinetic, and biological study of erlotinib in combination with paclitaxel and carboplatin in patients with advanced solid tumors
A Patnaik, D Wood, AW Tolcher, M Hamilton… - Clinical cancer …, 2006 - AACR
… of erlotinib in combination with paclitaxel and carboplatin on … pharmacokinetics of erlotinib,
paclitaxel, and carboplatin in … of erlotinib on the clearance of paclitaxel and carboplatin; (d) …
paclitaxel, and carboplatin in … of erlotinib on the clearance of paclitaxel and carboplatin; (d) …
Pharmacokinetic study of the phase III, randomized, double-blind, multicenter trial (TRIBUTE) of paclitaxel and carboplatin combined with erlotinib or placebo in …
HT Tran, RG Zinner, GR Blumenschein Jr… - Investigational new …, 2011 - Springer
… erlotinib with carboplatin and paclitaxel 6). In this previous study, there was no evidence of
a pharmacokinetic interaction between paclitaxel and erlotinib, … during erlotinib treatment. …
a pharmacokinetic interaction between paclitaxel and erlotinib, … during erlotinib treatment. …
Erlotinib added to carboplatin and paclitaxel as first-line treatment of ovarian cancer: a phase II study based on surgical reassessment
SV Blank, P Christos, JP Curtin, N Goldman… - Gynecologic …, 2010 - Elsevier
… kinase inhibitor erlotinib in combination with first-line carboplatin-paclitaxel chemotherapy
in … We found no evidence that addition of erlotinib to carboplatin-paclitaxel improved the …
in … We found no evidence that addition of erlotinib to carboplatin-paclitaxel improved the …
Paclitaxel/carboplatin plus bevacizumab/erlotinib in the first-line treatment of patients with carcinoma of unknown primary site
JD Hainsworth, DR Spigel, DS Thompson… - The …, 2009 - academic.oup.com
… use bevacizumab and erlotinib concurrently with paclitaxel and carboplatin in the … paclitaxel
and carboplatin. For patients felt to be benefiting from treatment, bevacizumab and erlotinib …
and carboplatin. For patients felt to be benefiting from treatment, bevacizumab and erlotinib …
Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma …
PA Jänne, X Wang, MA Socinski, J Crawford… - Journal of clinical …, 2012 - ascopubs.org
… kinase inhibitor (TKI) erlotinib is an effective treatment for … The efficacy of EGFR TKIs, including
erlotinib, is greatest in the … the role of adding erlotinib to first-line carboplatin and paclitaxel …
erlotinib, is greatest in the … the role of adding erlotinib to first-line carboplatin and paclitaxel …
Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non–small-cell lung cancer
… of erlotinib followed by carboplatin and paclitaxel) be compared with carboplatin and paclitaxel
… In the TRIBUTE trial, 495 former or current smokers receiving carboplatin and paclitaxel …
… In the TRIBUTE trial, 495 former or current smokers receiving carboplatin and paclitaxel …
Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: results …
AN Gordon, N Finkler, RP Edwards… - International Journal of …, 2005 - ijgc.bmj.com
… rate and safety profile of erlotinib HCl (erlotinib, Tarceva™, OSI-… Thirty-four patients received
150 mg erlotinib orally once daily … Erlotinib was generally well tolerated. The most frequent …
150 mg erlotinib orally once daily … Erlotinib was generally well tolerated. The most frequent …
Enhanced sensitivity to the HER1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib hydrochloride in chemotherapy-resistant tumor cell lines
Q Dai, YH Ling, M Lia, YY Zou, G Kroog, KK Iwata… - Clinical Cancer …, 2005 - AACR
… to erlotinib was observed in the doxorubicin-resistant human breast cancer cell line MCF-7,
paclitaxel-… The IC 50 values of erlotinib in the resistant cell lines were 2- to 20-fold lower than …
paclitaxel-… The IC 50 values of erlotinib in the resistant cell lines were 2- to 20-fold lower than …
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