… thiol groups are essential for NFkB inhibition by carotenoid derivatives. In conclusion, we
propose that electrophilic carotenoid derivatives contribute to cancer prevention as well as …

… radical products, which in turn undergo further transformation leading to a variety of secondary
β-carotene derivatives. These compounds may no longer act as antioxidants, and in fact …

… non-provitamin A carotenoids and their derivatives with retinoic … Likewise, nuclear factor-kappa
B (NF-κB) translocation may be … especially when ethanol reduced BCO2 activity [26], also …

… peonidin derivatives were … β-carotene bleaching method evaluated antioxidant activity
of selected fruit juices measuring the inhibitory effect of juices on coupled oxidation of β-carotene …

… by Amine Derivatives ture was incubated at 37C and induced with 1 mM IPTG when A600 Å
… aromatic residues in the acetylcholine bindcarotenoid cyclase activities. In this context, it is …

… extracellular signal-regulated protein kinases (ERK), c-Jun N-terminal kinases (JNK) and
p38], and the redox-sensitive transcription factors nuclear factor-kappa B (NF-κB) and c-Jun. …

… , ionones, and their derivatives represent a group of carotenoid-derived compounds (… novel
bioactivity of damascones and ionones as well as some of their functionalized derivatives (Fig…

… resulted in a significant increase in reactive oxygen species (ROS), which was accompanied
by a sustained elevation of NF-kappaB DNA-binding activity, increased expression of its …

… -kappa B and interferon regulatory factors, respectively. Furthermore, we found that β-carotene …
PMA, an ester derivative of phorbol diterpene from croton oil, is known to activate protein …

… We hypothesize that carotenoids or their oxidized derivatives interact with a network of
transcription factors that are activated by different ligands at low affinity and specificity. The …